BACKGROUND Disability Adjusted Life Years (DALYs) quantify the loss of healthy years of life due to dying prematurely and due to living with diseases and injuries. Current methods of attributing DALYs to underlying risk factors fall short on two main points. First, risk factor attribution methods often unjustly apply incidence-based population attributable fractions (PAFs) to prevalence-based d...

Salmonellosis, campylobacteriosis and listeriosis are food-borne diseases. We estimated and forecasted the number of cases of these three diseases in Belgium from 2012 to 2020, and calculated the corresponding number of disability-adjusted life years (DALYs). The salmonellosis time series was fitted with a Bai and Perron two-breakpoint model, while a dynamic linear model was used for campylobac...

Limits on health care resources mandate that resource-allocation decisions be guided by consideration of cost in relation to the associated expected benefits. It therefore leads to an increased demand for economic evaluation and medical technology assessment. Nowadays, cost-effectiveness analysis (CEA) has emerged as a favored analytic technique for economic evaluation in health care. Currently...

OBJECTIVES To estimate the burden of disease attributed to low fruit and vegetable intake by sex and age group in South Africa for the year 2000. DESIGN The analysis follows the World Health Organization comparative risk assessment (CRA) methodology. Population-attributable fractions were calculated from South African prevalence data from dietary surveys and applied to the revised South Afric...

There is an error in the fourth paragraph of the Discussion, second sentence. The correct sentence is: If we consider the combined burden attributable to S. enterica from all invasive (including iNTS, Salmonella Typhi and Salmonella Paratyphi A) and diarrheal infections, there were an estimated 21.2 million (95% UI 12.8–35.8 million) DALYs from all transmission sources and 8.76 million (95% UI ...

Disability-Adjusted Life Years (DALYs) and Quality-Adjusted Life Years (QALYs), which capture life expectancy and quality of the remaining life-years, are applied in a new method to measure socioeconomic impacts related to health. A 7-step methodology estimating the impact of health interventions based on DALYs, QALYs and functioning changes is presented. It relates the latter (1) to the EQ-5D-...

In order to target the most important cost components of gastroenteritis in The Netherlands and to indicate which change of policy yields the largest decrease in costs, the cost of illness of gastroenteritis and the number of Disability Adjusted Life Years (DALYs) in the Dutch population in 1999 were determined. The costs of gastroenteritis were estimated using data mainly from a community-base...

Ischemic heart disease (IHD) is the greatest single cause of mortality and loss of disability-adjusted life years (DALYs) worldwide, accounting for roughly 7 million deaths and 129 million DALYs annually. Cardiovascular disease exerts a significant economic toll, accounting for one third of a projected $47 trillion in economic losses to noncommunicable diseases (NCDs) for the next 20 years. Alt...

Cystic echinococcosis (CE) is an emerging zoonotic parasitic disease throughout the world. Human incidence and livestock prevalence data of CE were gathered from published literature and the Office International des Epizooties databases. Disability-adjusted life years (DALYs) and monetary losses, resulting from human and livestock CE, were calculated from recorded human and livestock cases. Alt...

OBJECTIVE To measure the economic burden of diabetes in Argentina by age, gender and region for the year 2005, in disability-adjusted life years (DALYs). METHODS DALYs were estimated by the sum of years of life lost due to premature death (YLL) and years of life lived with disability (YLD). RESULTS In the population studied (20 to 85 years), the burden of diabetes without complications was ...