Sir, Bioinformatics is a tool which can excavate any information, one wants to obtain. I found its implication in handling an emerging and highly pathogenic strain of Influenza virus, H5N1. The first influenza pandemic was happened in 1918 “Spanish flu” followed by Asian flu in 1957 caused by H2N2. Moreover, one million deaths were reported in Hong Kong due to H3N2 outbreak during 1968. The ant...

NEIBank is an integrated resource for genomics and bioinformatics in vision research. It includes expressed sequence tag (EST) data and sequence-verified cDNA clones for multiple eye tissues of several species, web-based access to human eye-specific SAGE data through EyeSAGE, and comprehensive, annotated databases of known human eye disease genes and candidate disease gene loci. All expression-...

ApiDB (http://ApiDB.org) represents a unified entry point for the NIH-funded Apicomplexan Bioinformatics Resource Center (BRC) that integrates numerous database resources and multiple data types. The phylum Apicomplexa comprises numerous veterinary and medically important parasitic protozoa including human pathogenic species of the genera Cryptosporidium, Plasmodium and Toxoplasma. ApiDB serves...

Since the initial sequencing of the human genome, many projects are underway to understand the effects of genetic variation between individuals. Predicting and understanding the downstream effects of genetic variation using computational methods are becoming increasingly important for single nucleotide polymorphism (SNP) selection in genetics studies and understanding the molecular basis of dis...

Identification of epitopes which invoke strong humoral responses is an essential issue in the field of immunology. Localizing epitopes by experimental methods is expensive in terms of time, cost, and effort; therefore, computational methods feature for its low cost and high speed was employed to predict B-cell epitopes. In this paper, we review the recent advance of bioinformatics resources and...

Genomic and post-genomic biological research has provided fine-grain insights into the molecular processes of life, but also threatens to drown biomedical researchers in data. Moreover, as new high-throughput technologies are developed, the types of data that are gathered en masse are diversifying. The need to collect, store and curate all this information in ways that allow its efficient retri...

This chapter provides guidelines for developing a university library collection for bioinformatics programs. The chapter discusses current research and scholarly communication trends in bioinformatics and their impact on information needs and information seeking behavior of bioinformaticians and, consequently, on collection development. It also discusses the criteria for making collection devel...

Structural Bioinformatics covers the prediction and analysis in-silico of biological molecular structures with the goal to understanding functional mechanisms at a molecular level. Due to the significant effort of the scientific community, this field has dramatically evolved over the recent years, in particular for proteins. The techniques available to predict and analyze protein structures are...

This completely computer-based module's purpose is to introduce students to bioinformatics resources. We present an easy-to-adopt module that weaves together several important bioinformatic tools so students can grasp how these tools are used in answering research questions. Students integrate information gathered from websites dealing with anatomy (Mouse Brain Library), quantitative trait locu...