Transcriptional regulatory network (TRN) reconstitution and deconstruction occur simultaneously during reprogramming; however, it remains unclear how the starting and targeting TRNs regulate the induction and suppression of peripheral genes. Here we analyzed the regulation using direct cell reprogramming from human dermal fibroblasts to monocytes as the platform. We simultaneously deconstructed...

Recently there has been interest in electroweak models on a five dimensional interval that break the symmetry without a higgs boson. By warping the metric of the interval it may be possible to avoid experimental bounds on extra W bosons and δρ. Five dimensional models necessarily require an explicit UV cut-off to remain perturbative, such as that provided by deconstruction. We study a simple de...

Many applications in computer graphics require fast and robust collision detection algorithms. The problem of simulating motion in an articulated chain has been well studied using both dynamic and kinematics techniques. This paper describes an efficient method for obstacle representation in the configuration space (C-space) for articulated chains. The method is based on the analytical deconstru...

This paper discusses the resources for deconstruction offered by cognitive science, drawing inspiration from David Gunkel’s work on topic (Deconstruction, MIT Press 2021). The gesture of is seen as having a positive impact development this interdisciplinary field challenging misleading dichotomies and examining its underlying assumptions, such symmetry integration.
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