Histoplasmosis is an endemic mycosis of the Americas, Africa, and Asia. In Spain, it is the most common imported endemic mycosis appearing in the literature, and its incidence is on the rise. Proper differential diagnosis of the disease must be taken into consideration by otorhinolaryngologists, as the clinical manifestations of histoplasmosis may simulate more prevalent diseases such as cancer...

dear editor,   mycosis fungoides is the most common type of cutaneous t cell lymphoma with a reported incidence of 0.5 cases per 100,000 people per year. 1 the cause of mycosis fungoides is still unknown; however genetic and environmental factors have been implicated as possible pathologic factors. 2 the disease might also be associated with human t cell lymphotropic virus type 1, 3 which is en...

Dear Editors: Pityriasis lichenoides-like mycosis fungoides (MF) is a rare variant of MF, presenting clinical findings pityriasis lichenoides (PL) but histological features MF [...]

BACKGROUND Recent years have seen an increase in the off-label use of photodynamic therapy for the treatment of a variety of skin diseases. Plaque-phase mycosis fungoides is among the most promising possibilities for the use of this treatment. OBJECTIVES To evaluate the treatment of plaque-phase mycosis fungoides with photodynamic therapy and compare the results obtained using fluorescence ph...

The epidemiological characteristics of paracoccidioidomycosis were reviewed and updated. The new endemic areas in Brazil were discussed in the section regarding the geographic distribution of the mycosis. Subclinical infection with Paracoccidioides brasiliensis was discussed on the basis of skin test surveys with antigens of the fungus, seroepidemiological studies, and disease cases outside Lat...

Administration of hematoporphyrin derivative i.v. followed by local exposure to red light has resulted in complete or partial response in 111 of 113 cutaneous or s.c. malignant lesions. Tumors treated have included carcinomas of the breast, colon, prostate, squamous cell, basal cell, and endometrium; malignant melanoma; mycosis fungoides; chondrosarcoma; and angiosarcoma. No type has been found...

The systemic fungus diseases are not common, and it is difficult to amass a significant number of patients with anyone specific deep mycosis in order to evaluate clinically any new chemotherapeutic agent. This review has attempted to assemble and summarize the present-day knowledge of the newer antifungal agents. Individual consideration is given to the systemic fungus diseases: coccidioidomyco...

We report a case of intraocular mycosis fungoides in a 48-year-old man. The patient presented with decreased visual acuity, white subretinal lesions, and vitritis. Post-mortem histopathology revealed malignant T cell infiltrates consistent with mycosis fungoides in the retina, vitreous, and between the retinal pigment epithelium (RPE) and Bruch's membrane Focal atrophy of the RPE, along with th...

CLINICAL CASE Our patient was a 37-year-old male with palpebral mycosis fungoides, the most common T-cell cutaneous lymphoma. He had been treated previously with topical corticosteroids. We treated him with Imiquimod cream (5%) three times a week. DISCUSSION A clinical improvement was obtained with this drug, so we believe immuno-modulating agents need to be considered in the treatment of pal...