BACKGROUND Degenerative lumbar scoliosis (DLS) progresses with aging after 50-60 years, and the genetic association of DLS remains largely unclear. In this study, the genetic association between collagen type II alpha 1 (COL2A1) gene and DLS was investigated. METHODS COL2A1 gene polymorphism was investigated in DLS subjects compared to healthy controls to investigate the possibility of its as...

OBJECTIVE To assess the predictive factors for subjective improvement with nonsurgical treatment in consecutive patients with lumbar spinal stenosis (LSS). MATERIALS AND METHODS Patients with LSS were enrolled from 17 medical centres in Japan. We followed up 274 patients (151 men; mean age, 71 ± 7.4 years) for 3 years. A multivariable logistic regression model was used to assess the predictiv...

Purpose: To determine the effect of degenerative disease of the lumbar spine on bone mineral density in the lumbar spine and femoral neck. Materials and Methods: We reviewed radiographs and dual energy x-ray absorptiometry scans of the lumbar spine and hip in 305 Caucasian women with suspected osteoporosis. One hundred and eighty-six patients remained after excluding women less than 40 years of...

STUDY DESIGN Retrospective cohort study. OBJECTIVE The aim of this study was to evaluate the clinical relevance of the SRS-Schwab classification for degenerative lumbar scoliosis (DLS). SUMMARY OF BACKGROUND DATA The SRS-Schwab classification has been presented and validated as a useful tool for adult spinal deformity (ASD). This classification includes various types of ASD (degenerative de...

Methods A 64 y/o, postmenopausal female was seen in the clinic for 10 one hour visits, spaced over 5 months. This patient was significantly concerned regarding the twenty degree progression of her curve over 3 years. Family history is significant for severe spinal stenosis. The patient was educated in safe back mechanics, as well as specific scoliosis stabilization exercises according to Schrot...

Background: The surgical treatment of adult scoliosis still presents many points of discussion. Methods: This study involved a total number of 21 DS patients (4 males and 17 females). All patients required long-segment pedicle screw fixation due to the coronal plane or sagittal plane balance. Postoperative follow-up and evaluation were performed. The balance of coronal and sagittal planes was i...

BACKGROUND Age-related sarcopenia can cause various forms of physical disabilities. We investigated how sarcopenia affects degenerative lumbar scoliosis (DLS) and lumbar spinal canal stenosis (LSCS). METHODS Subjects comprised 40 elderly women (mean age 74 years) with spinal disease whose chief complaints were low back pain and lower limb pain. They included 15 cases of DLS (mean 74.8 years) ...

Background: Due to the increase of life expectancy, the prevalence of degenerative spine diseases such as adult degenerative lumbar scoliosis (ADLS) has been increasingly more than before which is required appropriate control and management. Therefore, the present study was aimed to survey the result of surgery in ADLS patients in Shiraz (Iran). Methods: This is a preliminary report of 30 patie...