نتایج جستجو برای: degos disease
تعداد نتایج: 1490121 فیلتر نتایج به سال:
© 2014 The Authors. doi: 10.2340/00015555-1791 Journal Compilation © 2014 Acta Dermato-Venereologica. ISSN 0001-5555 Pityriasis lichenoides et varioriformis acuta (PLEVA), also known as Mucha-Habermann disease, is an uncommon, idiopathic, acquired dermatosis characterised by erythematous and scaly papules that are often accompanied by haemorrhagic and papulonecrotic lesions. The patient’s gener...
By Pierre Fenaux, Claude Chastang,† Sylvie Chevret, Miguel Sanz, Hervé Dombret, Eric Archimbaud,† Martin Fey, Consuelo Rayon, Françoise Huguet, Jean-Jacques Sotto, Claude Gardin, Pascale Cony Makhoul, Philippe Travade, Eric Solary, Nathalie Fegueux, Dominique Bordessoule, Jesus San Miguel, Harmut Link, Bernard Desablens, Aspasia Stamatoullas, E. Deconinck, Fréderic Maloisel, Sylvie Castaigne, C...
Rumi O-glucosylates the EGF repeats of a growing list of proteins essential in metazoan development, including Notch. Rumi is essential for Notch signaling, and Rumi dysregulation is linked to several human diseases. Despite Rumi's critical roles, it is unknown how Rumi glucosylates a serine of many but not all EGF repeats. Here we report crystal structures of Drosophila Rumi as binary and tern...
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