Background and Purpose: Epoxygenase metabolites of arachidonic acid are produced by several tissues and have been shown to inhibit in vitro platelet aggregation. The purpose of the present investigation was to determine whether 14,15or 8,9-epoxyeicosatrienoic acid, epoxygenase derivatives of arachidonic acid, affect the speed of platelet aggregation in in vivo mouse cerebral arterioles. Methods...

This study was performed to assess the clopidogrel activity in inhibition of platelet aggregation in suspected angina patients on a daily dosag of 75 mg of clopidogrel for at least 7 days. This clinical trial was conducted in the outpatients department of Cardiology, Post graduate Medical Institute, Lady Reading Hospital, Peshawar from 15th October 2007 to 20th December 2007. We included 105 su...

Neutrosophic sets are powerful logics designed to facilitate understanding of indeterminate and inconsistent information; many types of incomplete or complete information can be expressed as interval valued neutrosophic sets (IVNSs). This paper proposes improved aggregation operation rules for IVNSs, and extends the generalized weighted aggregation (GWA) operator to work congruently with IVNS d...

In wireless sensor networks (WSNs), data aggregation schemes have been extensively investigated in order to reduce energy and bandwidth consumptions. In this paper, we propose an application-aware data aggregation (AADA) scheme, which applies different aggregation policies adaptively, depending on the types of packets (i.e. real-time (RT) and non real-time (NRT) packets). Specifically, NRT pack...

Protein aggregation, where molecules assemble into dimers, trimers, tetramers, or larger multimers, is a common occurrence that can have devastating consequences. Biotherapeutic proteins, such as monoclonal antibodies, can give rise to severe immunological events as a result of aggregation. Therefore, quantitation and monitoring using size exclusion chromatography (SEC) are paramount during man...

A series of novel 2-aminopyrimidine and 2-Substituted-4,6-diaminopyrimidine derivatives have been synthesized and their anti platelet aggregation activities were assessed against ADP and arachidonic acid- induced platelet aggregation in human plasma using light transmission aggregometry. None of the compounds showed satisfactory activity against the aggregation induced by ADP. However, satisfac...

the probability that the commutator of two group elements is equal to a given element has been introduced in literature few years ago. several authors have investigated this notion with methods of the representation theory and with combinatorial techniques. here we illustrate that a wider context may be considered and show some structural restrictions on the group.

Many aggregation operators are studied to deal with multi-criteria group decision-making problems. Whenever information has two aspects, intuitionistic fuzzy sets and Pythagorean employed handle the information. However, q-rung orthopair more flexible suitable because they cover widely. The current paper primarily focuses on technique based prioritization robust Aczel–Alsina t-norm t-conorm. Th...

protein aggregation is a problem in biotechnology. high temperature is one of the most important reasons to enhance enzyme inactivation and aggregation in industrial systems. this work focuses on the effect of tio2 and sio2 nanoparticles on refolding and reactivation of lysozyme. in the presence of tio2 and sio2 nanoparticles, after enzyme heat treatment at 98◦c for 30 min, not only aggregates ...