OBJECTIVES There is still some controversy in the dental literature whether carbamide peroxide bleaching causes demineralization of teeth. One of the reasons for this controversy is that there is as yet no reliable, non-destructive in vitro method for assessing mineral loss in bleached teeth. The objective of this study was to investigate the possible demineralization effect of 10% carbamide pe...

Dental caries is a bacterially based disease that progresses when acid produced by bacterial action on dietary fermentable carbohydrates diffuses into the tooth and dissolves the mineral, that is, demineralization. Pathological factors including acidogenic bacteria (mutans streptococci and lactobacilli), salivary dysfunction, and dietary carbohydrates are related to caries progression. Protecti...

AIM To evaluate the effect of amorphous calcium phosphate (ACP)-containing pit and fissure sealant on inhibition of enamel demineralization in vitro. MATERIALS AND METHODS Enamel specimens (n = 75) were prepared using freshly extracted noncarious human third molars. Box-shaped cavities (8 × 2 × 2 mm) on the buccal or lingual surfaces were prepared and restored with resin-based sealant (Concis...

OBJECTIVE Although sucrose is considered the most cariogenic carbohydrate in the human diet, the question of how many exposures are needed to induce damage on the hard dental tissues remains unclear. To approach this question, different frequencies of daily sucrose exposure were tested on a relevant biological caries model. MATERIALS AND METHODS Biofilms of the Streptococcus mutans were forme...

different studies have reported contradictory results about the effect of osteoporosis on periodontal status. we performed this study to evaluate the periodontal status of menopausal women by methods with enough accuracy and confidence.this study was performed based on the evaluation of bone mineral density using dual energy x-ray absorptiometry in 2010. a total of 60 patients who met the inclu...

statement of the problem : enamel white spot lesions are one of the problems associated with fixed orthodontic treatment that compromise esthetics. porpuse the aim of this study was to evaluate the effect of fluoride varnish on the improvement of white spot lesions after fixed orthodontic treatment. materials and methods in this randomized clinical trial, 20 patients with at least two white spo...

OBJECTIVES To evaluate the effectiveness of fluoride in preventing white spot lesion (WSL) demineralization during orthodontic treatment and compare all modes of fluoride delivery. DATA SOURCES The search strategy for the review was carried out according to the standard Cochrane systematic review methodology. The following databases were searched for RCTs or CCTs: Cochrane Clinical Trials Reg...

This study was conducted to evaluate the effect of fluoride varnishes containing different calcium phosphate sources on demineralization of initial primary enamel lesions. Forty-eight sound primary incisors were completely coated with nail varnish except for two 1x1 mm windows before being placed in demineralizing solution for 4 days. After demineralization, one of the windows in each tooth was...

Objective The goal of this study was to evaluate the in vivo effects of a novel mouthwash on enamel remineralization. Materials and Methods Ten healthy volunteers wore removable intra-oral appliances for three study arms with duration of 5 days each. In 1 study arm, subjects used Oral Essentials Sensitivity FormulaR mouthwash; in another arm they used SensodyneR mouthwash, and in the third ar...

Mechanistic studies on demineralization-remineralization play a critical role in investigating caries pathogenicity, testing effects of new caries prevention methods, and developing new caries-preventing products. Simulating the cariogenic challenges in the mouth, various demineralization-remineralization models have been used for cariology research. This review aimed to provide an overview of ...