Vitiligo is a common dermatological disorder. A middle-aged woman with preexisting vitiligo was diagnosed with breast carcinoma. After surgery and chemotherapy she received regional radiotherapy. Six months after the completion of radiotherapy she developed depigmentation in the irradiated area. This article discusses the etiology for this phenomenon and the literature in this regard.

Gingival hyperpigmentation is mostly caused by the physiologic deposition of melanin by melanocytes. Melanin pigmentation of the gingiva is completely benign and does not present a medical problem. In "Gummy Smile" Patients, melanin gingival hyperpigmentation causes an esthetic problem and physiologic disturbances. Many methods are now available for depigmentation of the gingival. This paper re...

Acrodermatitis enteropathica is the clinical expression of congenital zinc deficiency and is now treated with supplemental zinc. This report details the ocular histopathology of a child who died before efficacious treatment was available. The findings include corneal epithelial thinning and loss of polarity, anterior corneal scarring and loss of Bowman's membrane, cataract formation, ciliary bo...

The word vitiligo is possibly derived from “Vitellius” meaning white leather patches. [1] This disease is acquired lack of pigmentation following the absence of epidermal melanocytes [1]. The destruction of melanocytes is the result of depigmented macules clinically seen in this disease. Although its cause is unknown, several theories have been presented such as autoimmunity, autocytotoxicity, ...

The dominant phenotype of greying with age in horses, caused by a 4.6-kb duplication in intron 6 of STX17, is associated with a high incidence of melanoma and vitiligo-like skin depigmentation. However, the progressive greying and the incidence of melanoma, vitiligo-like depigmentation, and amount of speckling in these horses do not follow a simple inheritance pattern. To understand their inher...

At the age of two years, Jeanett developed vitiligo within days of receiving her first MMR vaccine and the fourth injection of DTaP and IPV vaccines. Furthermore, at five years of age, she developed many more unpigmented spots on her body with acrofacial vitiligo, following receipt of the second injection of MMR and the fifth injection of DTaP and IPV vaccines. Jeanett’s susceptibility to devel...

Vitiligo is a pigmentation disorder involving 1% of the population. One of the first line depigmenting agents is monobenzyl ether of hydroquinone (MBEH). Repigmentation following sun exposure; however, can occur after successful treatment with MBEH. This study describes a 54-year-old gentleman who presented with a 7-year history of hyperpigmented lesions on his face following depigmentati...

It has been shown that certain symptoms in chicks, namely, exudative diathesis, yellow coloration of the adipose tissue, and encephalomalacia, and in rats, namely, yellowbrown coloration of the adipose tissue, and depigmentation of the incisors, depend upon the consumption of vitamin E-deficient diets rich in highly unsaturated fatty acids (Dam, 1944a, b ; Dam & Granados, 1945a, b ; Granados & ...