This work presents the desymmetrization of oxabenzonorbornadienes through (3+2) cycloaddition reaction with hydrazones using a chiral Brønsted acid such as BINOL-derived phosphoramide. catalyst appears most effective mediator for activation hydrazone via hydrazonium cation that reacts in fashion oxabenzonorbornadiene olefinic counterpart. Under optimized conditions, provided selectively exo pro...

Bacterial pathogens need to scavenge iron from their host for growth and proliferation during infection. They have evolved several strategies to do this, one being the biosynthesis and excretion of small, high-affinity iron chelators known as siderophores. The biosynthesis of siderophores is an important area of study, not only for potential therapeutic intervention but also to illuminate new e...