PurposeAlthough considered exceptional, radiation-induced arteriopathy in long-term breast cancer survivors involves three main arterial domains the irradiated volume, namely axillary-subclavian, coronary, and carotid. Stenosis of medium-large arteries is caused by “accelerated” atherosclerosis, particularly beyond 10 years after long-forgotten radiotherapy. The present review aims at summarizi...

OBJECTIVE To study the effect of systemic hyperbaric oxygenation (HBO) therapy on the healing course of nonischemic chronic diabetic foot ulcers. RESEARCH DESIGN AND METHODS From 1999 to 2000, 28 patients (average age 60.2 +/- 9.7 years, diabetes duration 18.2 +/- 6.6 years), of whom 87% had type 2 diabetes, demonstrating chronic Wagner grades I-III foot ulcers without clinical symptoms of ar...

We present a case report of patient with previously identified cerebral autosomal dominant arteriopathy subcortical infarcts and leukoencephalopathy (CADASIL), who was admitted due to coronavirus disease 2019 (COVID-19), confirmed by polymerase chain reaction computed tomography. Examination treatment these patients presents certain difficulties the large number thromboembolic complications cau...

Dolichoectasis is a dilative arteriopathy that can be seen in intracranial vertebral and basilar arteries people with hypertension advanced age. Although most cases are asymptomatic, cerebral ischemia, bleeding or compression may occur. The diagnosis of VBD was made by catheter angiography before; while MR the sensitive imaging method today. In addition, differential aneurysm/other vascular pro...

Human immunodeficiency virus (HIV)-associated cerebral aneurysmal arteriopathy is described in the pediatric medical literature and features diffuse fusiform aneurysms of the arteries of the circle of Willis. We present the first report (to our knowledge) of this disease entity in an adult, a 29-year-old woman with acquired immunodeficiency syndrome who presented with subarachnoid hemorrhage.

The occurrence of pulmonary arteriosclerosis and arteriolosclerosis has long been recognized. Such structural changes in the pulmonary vasculature have usually been considered to represent an adaptation to alterations in the haemodynamics of the lesser circulation. In particular, their presence has been related to pulmonary hypertension, and they have been compared to the changes which occur in...

Vascular smooth muscle cell (VSMC) differentiation and proliferation are two important physiological processes during vascular development. The phenotypic alteration from differentiated to proliferative VSMC contributes to the development of several major cardiovascular diseases including atherosclerosis, hypertension, restenosis after angioplasty or bypass, diabetic vascular complications, and...

BACKGROUND AND PURPOSE Recently, in a mouse model of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy, a monogenic cerebral small vessel disease, intramyelinic edema was detected in the white matter (WM) early during the course of the disease. We hypothesized that if this mechanism holds true in patients, it would translate in larger WM volume. We aimed...

Primary pulmonary hypertension with plexiform vascular changes in the lungs and liver cirrhosis is a rare combination of unclear pathogenesis. Until now, the real prevalence has not been known. The diagnosis of this association is usually made retrospectively. The criteria are morphological--that is, right ventricular hypertrophy and the characteristic pulmonary arterial lesions, as well as cli...

Calcific uremic arteriopathy (CUA) is a rare but potentially life-threatening complication of end-stage renal disease (ESRD) and secondary hyperparathyroidism. It typically presents with ischemic necrosis involving areas of adiposity in the body mainly the trunk, buttocks, or proximal extremity. Patients can also present with digital ischemia and more rarely penile gangrene. The pathogenesis of...