OBJECTIVE To describe the clinical outcome of infants born to mothers with gestational diabetes mellitus (GDM) and preexisting insulin-dependent diabetes mellitus (IDDM). SETTING A tertiary care regional perinatal center with a specialized diabetes-in-pregnancy program. DESIGN Case series. RESULTS Five hundred thirty infants were born to 332 women with GDM and 177 women with IDDM. Thirty-...

Infants of diabetic mothers are significantly at higher risk for major congenital malformations, with cardiovascular anomalies that is the most frequent. In this study, we presented a rare case of dextrocardia and situs inversus totalis (mirror-image dextrocardia) with multiple congenital heart anomalies who was born from a diabetic mother.

DURING the last two decades the outcome of pregnancy in the diabetic has improved greatly. In the Royal Maternity Hospital, Belfast, for example, the total fetal loss and perinatal mortality during the years 1972-78 have been 4.3 and 3.2 per cent respectively, whereas in earlier years figures well in excess of 10 per cent were common everywhere. In view of this the contribution of congenital ma...

Heart. London, Wildwood House, 1974 7. Glass DC: Behaviour Patterns, Stress and Coronary Disease. New York, John Wiley & Sons, 1977 8. Nixon PGF: The human function curve, with special reference to cardiovascular disorders. Practitioner 217: 765, 935, 1976 9. Nixon PGF: The responsibility of the cardiological mapmaker (editorial). Am Heart J 1980. In press 10. Cassel J: The contribution of the ...

is two to five times greater in infants of diabetic mothers than in other infants. Poor glycemic control in the first trimester during organogenesis is thought to be the major reason for congenital malformations (1). The most frequently seen types of malformations in infants of diabetic mothers involve the cardiovascular, skeletal, central nervous, gastrointestinal and genitourinary systems, wi...

The results of a follow-up study of infants of diabetic mothers are presented. The antenatal care of all such mothers was supervised in a combined clinic by obstetricians and physicians, and good diabetic control was achieved in most of them. 51 mothers delivered 73 infants, all liveborn, between the years 1964 and 1972 inclusive at Hammersmith Hospital. There were no fetal deaths. 66 infants s...

CONTEXT/OBJECTIVE Not much is known about the implication of adipokines and different cytokines in gestational diabetes mellitus (GDM) and macrosomia. The purpose of this study was to assess the profile of these hormones and cytokines in macrosomic babies, born to gestational diabetic women. DESIGN/SUBJECTS A total of 59 women (age, 19-42 yr) suffering from GDM with their macrosomic babies (4...