INTRODUCTION The aim of the paper is to examine the incidence and the rate of cardio respiratory disorders in mothers of newborns with diabetes mellitus in pregnancy as well as their influence on the perinatal outcome. MATERIAL AND METHODS A prospective and random study included 102 newborns, 31 newborns of mothers with glucose homeostasis disorder (group I) and 71 newborns of healthy mothers...

Pregnancy in insulin-dependent diabetes mellitus is associated with a greater incidence of fetal abnormality. Animal studies suggested that increased free-radical production and antioxidant depletion may contribute to this risk. The objective of this work was to evaluate oxidative stress and antioxidant capacity in hypertensive, diabetics, and healthy control women during labor. Simultaneous de...

BACKGROUND Previous studies carried out in our laboratories have demonstrated impaired drug permeation in diabetic animals. In this study the permeation of diazepam (after a single dose of 5 mg/day, administered intramuscularly) will be investigated in diabetic and hypertensive pregnant women. METHODS A total 75 pregnant women were divided into three groups: group 1 (healthy control, n = 31),...

In the United States, depending on the diagnosis criteria used, 135,000– 200,000 women annually develop gestational diabetes mellitus (GDM), adding to the number of pregnant women who already have either type 1 or type 2 diabetes. There has also been a significant increase (~ 33%) in the incidence of type 2 diabetes with its presumed parallel risk for obesity in addition to the development of a...

In the United States, depending on the diagnosis criteria used, 135,000– 200,000 women annually develop gestational diabetes mellitus (GDM), adding to the number of pregnant women who already have either type 1 or type 2 diabetes. There has also been a significant increase (~ 33%) in the incidence of type 2 diabetes with its presumed parallel risk for obesity in addition to the development of a...

background and purpose: social support is considered as a facilitator of health behaviors in women. this study aimed to evaluate and compare the status of social support and its associated dimensions in pregnant and non-pregnant women. methods: this analytical study was conducted on 310 pregnant and non-pregnant women referring to the health-care centers of zarqan city in shiraz, iran in 2011. ...

Pregnancy in women with type 1 diabetes is associated with poor maternal and neonatal outcomes. However, the risk of these outcomes has never been evaluated in an Asian national population. In this work, we report the maternal and fetal outcomes of pregnant women with type 1 diabetes in Taiwan. A total of 2,350,339 pregnancy records created between 2001 and 2012 were obtained from the National ...

BACKGROUND Metformin reduces maternal and neonatal weight gain in gestational diabetes mellitus; however, this effect is poorly investigated in non-diabetic women. OBJECTIVE We performed this meta-analysis to investigate the effect of metformin intake during pregnancy on maternal and neonatal outcomes in obese non-diabetic women. MATERIALS AND METHODS We searched Medline, EMBASE, and Cochra...

Apoptosis and its associated regulatory mechanisms are physiological events crucial to the maintenance of placental homeostasis; imbalance of these processes, however, such as occurs under various pathological conditions, may compromise placenta function and, consequently, pregnancy success. Increased apoptosis occurs in the placentas of pregnant women with several developmental disabilities, w...