OBJECTIVES: The aim of this study was to compare the expression levels of serum miRNAs in diabetic retinopathy and type 2 diabetes mellitus. METHODS: Serum miRNA expression profiles from diabetic retinopathy cases (type 2 diabetes mellitus patients with diabetic retinopathy) and type 2 diabetes mellitus controls (type 2 diabetes mellitus patients without diabetic retinopathy) were examined by...

Diabetic retinopathy is one of the most common devastating complications of diabetes. Currently there are no accepted drug treatments for diabetic retinopathy and laser therapy is the most accepted treatment option. Biochemical and physiological changes that occur very early in the retina of diabetic patients are the major signaling determinants of future damage to the retina. However, drug tre...

Aim: To study the relationship between serum Vitamin D levels and severity of Diabetic Retinopathy. Materials Methods: This cross-sectional was conducted on 346 subjects. The cases were divided into three groups, group A comprised 180 type 2 diabetic patients with retinopathy, B 86 without retinopathy (no DR) C age gender matched 80 healthy non controls. Group further A1 consisting 84 prolifera...

Abstract Diabetic retinopathy is a neurovascular complication of diabetes which an avoidable cause sight loss. Since the introduction screening for diabetic in UK along with improving treatments both and it no longer leading blindness UK. Screening detects at early stage when optimisation blood glucose, pressure cholesterol are effective reducing progression retinopathy. Once proliferative or m...

levels in the metabolic derangement of diabetes. N Engl J. Med 1984;310: 810-5. 19 Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM. Serum IGF-1 concentration in diabetic retinopathy. Diabetic Med 1988;5:356-60. 20 Sharp PS, Fallon TJ, Brazier OJ, Sandler L, Joplin GF, Kohner EM. Long term follow up of patients who underwent yttrium-90 pituitary implantation for treatment of proliferative ret...

We carried out a cross-sectional analytical survey using data from patients who had done Fluorescein Angiography at the Yaounde Central Hospital Diabetic Retinopathy Prevention and Management Project between October 2007 and January 2010 to identify the risk factors, incidence and severity of different types of diabetic retinopathy. Data from 239 males (57.0%) and 180 females (43.0%) with diabe...

The course of cystoid macular oedema (CMO) following extracapsular cataract extraction with posterior chamber intraocular lens implantation was prospectively studied in 44 eyes of 44 consecutive diabetic patients without preoperative CMO. In 50% of eyes CMO was observed 6 weeks after surgery and in 25% was still present at 1 year. The preoperative presence of diabetic retinopathy significantly ...

Retinopathy and nephropathy are common late type 1 diabetes mellitus (T1D) complications. In this study we investigated whether individual differences in 4 candidate genes significantly contribute to development and progression of late complications in T1D patients. We examined 121 patients for the presence of diabetic retinopathy and nephropathy. We genotyped variants in vitamin D receptor (VD...

OBJECTIVE Stimulation of the retina with flickering light increases retinal vessel diameters in humans. Nitric oxide is a mediator of the retinal vasodilation to flicker. The reduction of vasodilation is considered an endothelial dysfunction. We investigated the response of retinal vessels to flickering light in diabetic patients in different stages of diabetic retinopathy. RESEARCH DESIGN AN...

 Background: Diabetes is a common metabolic disorder leading to the development of many complications, among which diabetic retinopathy and macular edema are the most significant. These complications can contribute to blindness if not diagnosed or treated properly, and several studies have been conducted to evaluate the methods for the prevention or slowing down their progression. Ther...