Acid aspiration leads to thromboxane-dependent lung neutrophil sequestration associated with microvascular permeability increase. Leukotriene B4 (LTB4) is postulated to be a cofactor in the thromboxane-induced inflammatory response. This study tests the interaction between LTB4 and thromboxane, focusing on LTB4 induction of thromboxane-dependent lung neutrophil sequestration after acid aspirati...

Lymphatic filariasis is endemic to tropical countries and is the most common cause of acquired lymphedema in the world. Wuchereria bancrofti is the main etiological agent responsible. While the presentation of filariasis in limbs is common, isolated presentation as a single enlarged lymph node in the neck is very rare. We describe a 48-year-old Indian woman, who presented with a hard lymph node...

lymphatic filariasis is endemic to tropical countries and is the most common cause of acquired lymphedema in the world. wuchereria bancrofti is the main etiological agent responsible. while the presentation of filariasis in limbs is common, isolated presentation as a single enlarged lymph node in the neck is very rare. we describe a 48-year-old indian woman, who presented with a hard lymph node...

OBJECTIVE The aim of this study was to elucidate the roles of knowledge related to lymphatic filariasis (LF), contributions of taking roles in community activities to eradicate LF and participation in traditional village forums in adherence to mass drug administration (MDA) in a preventive chemotherapy program targeted at the community residents. MATERIALS AND METHODS A survey on ingestion of...

We explored the practicality of integrating surveillance for soil-transmitted helminthiasis (STH, assessed by Kato-Katz) with transmission assessment surveys for lymphatic filariasis (LF) in two evaluation units (EUs) in Gampaha district, Sri Lanka (population 2.3 million). The surveys were performed 6 years after five annual rounds of mass drug administration with diethylcarbamazine and albend...

A successful experience of lymphatic filariasis control in the Republic of Korea is briefly reviewed. Filariasis in the Republic of Korea was exclusively caused by infection with Brugia malayi. Over the past several decades from the 1950s to 2006, many investigators exerted their efforts to detection, treatment, and follow-up of filariasis patients in endemic areas, and to control filariasis. M...

BACKGROUND This study employed various monitoring methods to assess the impact of repeated rounds of mass drug administration (MDA) on bancroftian filariasis in Papua New Guinea, which has the largest filariasis problem in the Pacific region. METHODOLOGY/PRINCIPAL FINDINGS Residents of rural villages near Madang were studied prior to and one year after each of three rounds of MDA with diethyl...