backgrounds and aims: the protozoan parasites of the genus leishmania can be stated as the causative agents of the various clinical diseases. fetal calf serum (fcs) is the major part of the leishmania culture media, which is the most expensive ingredient in these media. the coconut water is packed with nutrients that yield an array of health benefits. materials and methods: in the present study...

Introduction. Primary cutaneous CD4+ lymphoproliferative disorder of small and medium cells (PC T-LPD small/medium cell) is a new entity identified in the WHO classification published 2017. The aim research was to characterize morphological immunohistochemical features PC cell. Materials methods. study examined 28 skin biopsies from 13 males 15 females with cell using histological Results. We d...

BACKGROUND Cutaneous vasculitis has been mainly associated with hematologic cancer. The association of solid neoplasms with cutaneous paraneoplastic vasculitis is rare. We report a case of cutaneous leucocytoclastic vasculitis that revealed a gastric adenocarcinoma. CASE REPORT A 72-year-old man presented with an acute diffuse polymorphic eruption, with erythematous, vesicular, and necrotic l...

BACKGROUND Cutaneous mastocytosis is a disorder characterized by the proliferation of mast cells in the skin. Melanoma inhibitory activity (MIA) is a serum marker for malignant melanoma. However, it has not been known on MIA expression of cutaneous mastocytosis. METHODS We investigated the expression of MIA in 4 child patients with cutaneous mastocytosis immunohistochemically and serum MIA le...

BACKGROUND Cutaneous metastasis of gastric adenocarcinoma is rare and usually presents in men, as nodules over the abdomen. We present the case of a woman with cutaneous metastasis of gastric adenocarcinoma showing unusual clinicopathological features. CASE REPORT A 37-year-old woman developed florid cutaneous metastasis over the skin of the left breast two years after total gastrectomy for a...

This report describes clinical findings of a 28-year old female patient presented with non-healing digit ulcer and Raynaud’s phenomenon. Upon investigation was found to have high eosinophil count alongside hypocomplementemia. diagnosed diffuse cutaneous systemic sclerosis started on therapy; her other laboratory were attributed coinciding helminthic infection. case suggests the possibility havi...

Diffüz kutanöz nörofibromlar, çocuklarda ve genç erişkinlerde görülen nadir bir nörofibroma varyantıdır. Bu lezyonlar kutanöz-subkutanöz yerleşimli olup yüzeysel olarak karşımıza çıkarlar. Derin tutulumu olmayan periferik sinirlerden ortaya çıkarlar veya derin pleksiform nörofibromun uzanımını temsil edebilirler. Pleomorfik nörofibrom ile diffüz nörofibromu ayırmak önemlidir, çünkü pleomorfik n...

Serum IgE levels and the expression of low affinity receptor for IgE (Fc epsilon RII/CD23) are increased in cutaneous leishmaniasis. The ligation of CD23 receptor by IgE-anti-IgE immune complexes results in nitric oxide (NO) production, which is a critical leishmanicidal factor. Human monocytes/macrophages express Fc epsilon RII/CD23 after activation with IFN-gamma and IL-4. In the present stud...