BACKGROUND AND PURPOSE Low birth weight preterm infants are at high risk of brain injury, particularly injury to the white matter. Diffusion tensor imaging is thought to be more sensitive than conventional MR imaging for detecting subtle white matter abnormalities. The objective of this study was to examine whether diffusion tensor imaging could detect abnormalities that may be associated with ...

OBJECTIVE/BACKGROUND The majority of multiple sclerosis patients experience impaired walking ability, which impacts quality of life. Timed 25-foot walk is commonly used to gauge gait impairment but results can be broadly variable. Objective biological markers that correlate closely with patients' disability are needed. Diffusion tensor imaging, quantifying fiber tract integrity, might provide s...

We present an anisotropic diffusion model for volumetric image filtering. Our 3D anisotropic diffusion tensor is constructed to enhance 1D features (curves) and 2D features(surfaces). Bilateral prefiltering is employed to construct more accurate anisotropic diffusion tensor. An efficient parallel implementation has been done on a PC cluster, the performance and speed-up are reported also.

J. Lee, A. L. Alexander Medical Physics, University of Wisconsin, Madison, WI, United States Background/Introduction Diffusion tensor MRI and the associated measures, such as FA, trace {D}, and eigenvector direction, are highly sensitive to image measurement noise. The main strategy to decrease noise sensitivity is to employ uniformly distributed diffusion encoding directions with a diffusion-w...

Diffusion Tensor Magnetic Resonance Imaging (DT-MRI or DTI) is emerging as an important technology for elucidating the internal structure of the brain and for diagnosing conditions affecting the integrity of nervous tissue. DTI measurements of the brain exploit the fact that the network of fibers has a characteristic microstructure that constrains the diffusion of water molecules within it. The...

PHILIPP HENDRIX, CHRISTOPH J. GRIESSENAUER, JULIEN COHEN-ADAD, SHANMUGANATHAN RAJASEKARAN, KEITH A. CAULEY, MOHAMMADALI M. SHOJA, PARHAM PEZESHK, AND R. SHANE TUBBS Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, Alabama Department of Biomedical Engineering, Ecole Polytechnique de Montreal, Quebec, Canada Department of Orthopaedic and Spine Surgery, Ganga Hospital, ...

SUMMARY Conventional MR imaging, MR spectroscopy, diffusion-weighted imaging, and diffusion tensor imaging were performed in a 5-month-old male patient with mitochondrial encephalomyopathy. On conventional T2-weighted MR images, symmetric, confluent high signal intensity was found in the temporoparietal white matter. A large lactate peak and decreased N-acetylaspartate were found in this region...

Multiple sclerosis is characterized by inflammatory demyelination and irreversible axonal injury leading to permanent neurological disabilities. Diffusion tensor imaging demonstrates an improved capability over standard magnetic resonance imaging to differentiate axon from myelin pathologies. However, the increased cellularity and vasogenic oedema associated with inflammation cannot be detected...