BACKGROUND The hippocampus undergoes apoptosis in experimental pneumococcal meningitis leading to neurofunctional deficits in learning and memory function. The aim of the present study was 1) to investigate hippocampal apparent diffusion coefficient (ADC) and volume with MRI during the course of experimental pneumococcal meningitis, 2) to explore the influence of accompanying bacteremia on hipp...

Abstract. We study the phase field method for the volume preserving mean curvature flow. Given an initial data which is a measure-theoretic boundary of a Caccioppoli set with a suitable density bound, we prove the existence of the weak solution for the volume preserving mean curvature flow via the reaction diffusion equation with a nonlocal term. We also show the monotonicity formula for the re...

Hyperspectral images taken from aircraft or satellites contain information hundreds of spectral bands, within which lie latent lower-dimensional structures that can be exploited for classifying vegetation and other materials. A disadvantage working with hyperspectral is that, due to an inherent trade-off between spatial resolution, they have a relatively coarse scale, meaning single pixels may ...

Volume segmentation is an important part of medical diagnostics, and fast solutions which nevertheless can handle large datasets are required. This paper presents a diffusion-based method that can be used for volume smoothing and segmentation purposes, and has been implemented on the GPU in order to achieve interactive performance. We describe the nonlinear isotropic and anisotropic diffusion m...

Fluorescence correlation spectroscopy (FCS) is a powerful technique for measuring low concentrations of fluorescent molecules and their diffusion constants. In the standard case, fluorescence fluctuations are measured in an open detection volume defined by the confocal optics. However, if FCS measurements are carried out in cellular processes that confine the detection volume, the standard FCS ...

1. GENERAL FORM OF FINITE VOLUME METHODS We consider vertex-centered finite volume methods for solving diffusion type elliptic equation (1) −∇ · (K∇u) = f in Ω, with suitable Dirichlet or Neumann boundary conditions. Here Ω ⊂ R is a polyhedral domain (d ≥ 2), the diffusion coefficient K(x) is a d× d symmetric matrix function that is uniformly positive definite on Ω with components in L∞(Ω), and...

BACKGROUND AND PURPOSE This study examines whether lesion shape documented on magnetic resonance diffusion-weighted imaging during acute stroke improves the prediction of the final infarct volume compared with lesion volume only. METHODS Diffusion-weighted imaging data and clinical information were retrospectively reviewed in 110 consecutive patients who underwent (n=67) or not (n=43) thrombo...