Treatment of 5-(tert-butyldimethylsilyl)-2,3-O-isopropylidene-D-ribose with lithium acetylides gave mixtures of syn- and anti-alkynols 2a-2c which were separated following protection as methoxymethyl ethers. These were converted to the corresponding iodides which underwent 6-exo-dig radical cyclisation to afford chiral cyclohexanes and carbasugars. Oxidation of the primary alcohols 6a-b gave th...

Data mining implies "digging through tons of data" to uncover implicit information. Software defect is an essential characteristic of software development process, offering much information about software quality assurance. Based on the information supplied by defects, it can help a software team with capability of software quality assurance. In order to dig through lots of defects to uncover i...

The objective of this observational cohort study was to characterize the pattern rumination time (RT), physical activity (PA), and lying (LT) monitored by an automated health monitoring system, based on ear-attached sensor, immediately before, during, after clinical diagnosis (CD) metabolic-digestive disorders. Sensor data were collected from 820 lactating Holstein cows daily calving up 21 DIM ...

Combining dispersion measures, distances and emission measures for 157 pulsars lying above | b |> 5 and between 60 < l < 360 we find the mean volume filling factor (f̄v) of the diffused ionized gas in the Milky Way. This filling factor is inversely related to the mean electron density (n̄c) in the clouds, f̄v = (0.0184± 0.0014)n̄c , implying a nearly constant average electron density distribution w...

In a simple procedure, the intramolecular hydroarylation of N-propargyl-pyrrole-2-carboxamides was accomplished with the aid of gold(III) catalysis. The reaction led to differently substituted pyrrolo[2,3-c]pyridine and pyrrolo[3,2-c]pyridine derivatives arising either from direct cyclization or from a formal rearrangement of the carboxamide group. Terminal alkynes are essential to achieve bicy...

For there are few samples of water inrush from coal floor, how to dig wider information under the circumstance of limited sample data is to improve the prediction accuracy of water inrush form coal floor. Therefore, prediction model of water inrush is established based on correlation analysis and support vector machine (SVM). Not only does the model simplify the influenced indexes to construct ...

We report that the 2-phosphaethynolate anion (PCO(-)) reacts with propargylamines in the presence of a proton source to afford novel N-derivatized phosphinecarboxamides bearing alkyne functionalities. Deprotonation of these species gives rise to novel five- and six-membered anionic heterocycles resulting from intramolecular nucleophilic attack of the resulting phosphide at the alkyne functional...