BACKGROUND In recent years, especially after the development of sophisticated metagenomic studies, research on the intestinal microbiota has increased, radically transforming our knowledge about the microbiome and its association with health maintenance and disease development in humans. Increasing evidence has shown that a permanent alteration in microbiota composition or function (dysbiosis) ...

INTRODUCTION Helicobacter pylori (H. pylori) infection affects approximately half of the world’s population. Unless eradicated, it remains in the stomach throughout life. After 1983, discovery of H. pylori as persistent resident of gastric mucosa, changed the traditional thoughts and perspectives regarding (i) having sterile stomach lifelong, (ii) infectious potential links existence with vario...

Celiac disease; is an autoimmune digestive system disease characterized by chronic intestinal inflammation and villus antrophy triggered dietary gluten genetically susceptible individuals. Diagnosis based on serological tests small bowel biopsy. Because of the diversity in clinical features disease, various patient profile non-standardized tests, it difficult to diagnose celiac disease. Sensiti...

Crohn’s disease is an inflammatory of the digestive system that affects children and adults. The cause unknown, but a combination genetic predisposition environmental factors suspected. Symptoms are usually mouth sores, fatigue, diarrhea, abdominal pain, weight loss, fever. Patients may also have symptoms outside system: skin rash, joint red eyes, liver problems.

BACKGROUND Digestive cancers are common malignancies worldwide, however there are few effective prognostic markers available. In this study we comprehensively investigated the prognostic significance of ZEB1 and ZEB2 in digestive cancers. METHODS Electronic databases were searched and studies met the selection criteria were included. Study information was recorded and quality assessment was p...

OBJECTIVES The aim of this study was to explore the characteristics of digestive organ cancer mortality and the potential years of life lost in Inner Mongolia, and to provide evidence for the prevention of digestive organ cancers. METHODS Using data from the Death Registry System from 2009 to 2012, we classified male and female cancer deaths according to the International Classification of Di...

The relationship between biliary tract inflammation (BTI) and digestive system cancers is unclear. This study aimed to evaluate the association between BTI and the risks of digestive system cancers.Using the Taiwan National Health Insurance claims data, information on a cohort of patients diagnosed with BTI (n = 4398) between 2000 and 2009 was collected. A comparison cohort of sex-, age-, and i...

Twelve patient information leaflets concerning common gastrointestinal diseases were produced by the British Digestive Foundation and evaluated to determine whether patients knew more about their disease if they received a leaflet. Eleven hundred and fifty patients attending gastroenterology clinics in the United Kingdom were assessed by postal questionnaire of whom half had received a leaflet ...

Digestive system malignancies are quite common, accounting for 25% of deaths from cancer in the European Union. Various etiological factors of carcinogenesis include hereditary mutations and susceptibility polymorphisms, inflammation due to infectious agents, environmental and dietary factors. Transgenic, knockout or mutant animal models are very useful in reproducing cancers of the digestive t...

To examine equity in one aspect of care provision in the Veterans Health Administration, this study analyzed factors associated with receipt of coronary artery bypass graft (CABG), vascular, hip/knee, or digestive system surgeries during FY2006-2009. A random sample of patients (N = 317, 072) included 9% with depression, 17% African-American patients, 5% Hispanics, and 5% women. In the four-yea...