Prostaglandins have stimulative influence on the human uterus and therefore were introduced to medical treatment in reproductive healthcare as labor inductors or abortifacients. The UHPLC-ESI-QqQ-MS/MS method was developed for six prostaglandins: carboprost, cloprostenol, dinoprost (PGF2α), dinoprostone (PGE2), misoprostol sulprostone (substances pregnancy termination) pharmaceutical samples ap...

Given a smooth projective curve C defined over Q and given two elliptic surfaces E1 −→ C and E2 −→ C along with sections Pi, Qi of Ei (for i = 1, 2), we prove that if there exist infinitely many t ∈ C(Q) such that for some integers m1,t,m2,t, we have that [mi,t](Pi)t = (Qi)t on Ei (for i = 1, 2), then at least one of the following conclusions must hold: either (i) there exists an isogeny ψ : E1...

Xibin Liang,1 Qian Wang,1 Tracey Hand,1 Liejun Wu,1 Richard M. Breyer,3 Thomas J. Montine,4 and Katrin Andreasson1,2 Departments of 1Neurology and 2Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, 3Department of Medicine, Division of Nephrology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, and 4Department of Pathology, University of ...

The life-cycle model is a standard theoretical framework for studying savings and wealth inequality. This paper shows that life-cycle models have di¢ culties accounting for the empirical relationship between lifetime earnings and household wealth. Quantitative life-cycle models imply a far tighter relationship between earnings and wealth than is observed in U.S. data. As a result, life-cycle mo...

The anaphase-promoting complex (APC) coordinates mitosis and G1 by sequentially promoting the degradation of key cell-cycle regulators. Following the degradation of its substrates in G1, the APC catalyzes the autoubiquitination of its E2 UbcH10. This stabilizes cyclin A and allows it to inactivate APC(Cdh1). How the APC establishes this complex temporal sequence of ubiquitinations, referred to ...

Aim: To compare effectiveness and safety of double balloon catheter prostaglandins for induction labor. Methods: an observational ambidirectional cohort study was conducted at a tertiary care university hospital. A total 666 women with Bishop score ≤6 requiring labor were included. 418 patients compared retrospective 248 induced prostaglandins, either misoprostol or dinoprostone. Perinatal outc...