BACKGROUND Diabetic patients may have a higher risk of gastric cancer. However, whether they have a higher incidence of Helicobacter pylori (HP) eradication is not known. Furthermore, whether insulin use in patients with type 2 diabetes may be associated with a higher incidence of HP eradication has not been investigated. METHODS This is a retrospective cohort study. The reimbursement databas...

Primary esophageal lymphoma is an extremely rare disease. We report a 76-year-old woman with esophageal lymphoma who achieved remission after Helicobacter pylori (HP) eradication. Esophagogastroduodenoscopy (EGD) revealed a mass in the lower esophagus, and she was diagnosed with stage IE mucosa-associated lymphoid tissue (MALT) lymphoma. She rejected any anti-lymphoma treatment except for HP er...

BACKGROUND The detection of wild poliovirus in Israeli sewage in May 2013 led the health authorities to vaccinate children with OPV (Oral Polio Vaccine). Shelly Kamin-Friedman explored the legal and ethical dimensions of this policy. This commentary makes three claims: (1) Mandatory vaccination is a valid exercise of the state's police powers to protect the common good. (2) A disease eradicatio...

The outgoing Director-General of the World Health Organization, Gro Harlem Brundtland, has successfully returned health issues to the international arena. The new Director-General will have to cope with reduced control over funding, debate over WHO's mandate, and the relationships between WHO and other organisations. Despite the broad role described in WHO's constitution, many groups see WHO's ...

The SIR (susceptible-infectious-resistant) and SIS (susceptible-infectious-susceptible) frameworks for infectious disease have been extensively studied and successfully applied. They implicitly assume the upper and lower limits of the range of possibilities for host immune response. However, the majority of infections do not fall into either of these extreme categories. We combine two general a...

Dracunculiasis is a disease caused by a parasite transmitted through infected drinking water. The International Drinking Water Supply and Sanitation Decade (1981-1990), provided a unique opportunity to eliminate the disease. The strategy of the eradication campaign was based on provision of safe drinking water supply, intensified case containment and health education. An appropriate epidemiolog...

Bovine tuberculosis is a chronic bacterial disease of cattle that occasionally affects other species of mammals. This disease is a significant zoonosis that can spread to humans, typically by the inhalation of aerosols or the ingestion of unpasteurized milk. In developed countries, eradication programs have reduced or eliminated tuberculosis in cattle, and human disease is now rare; however, re...

I. Role of Surveillance in Disease Elimination Programs In routine disease control programs, traditional, passive disease surveillance systems are usually adequate to meet program demands despite their limitations. In contrast, in disease elimination or eradication programs, routine surveillance activities are inadequate once the goal is near. In advanced disease elimination and eradication pro...

To the Editor: In “Reemergence of Plasmodium vivax malaria in the Republic of Korea” (1), the term eradication was, in my judgment, inappropriately used. In 1981, Yekutiel proposed that eradication is “The purposeful reduction of specific disease prevalence to the point of continued absence of transmission within a specified area by means of a time limited campaign” (2). In 1984, Hinman propose...

CONTEXT Helicobacter pylori eradication has become the standard treatment for peptic ulcer disease. Triple therapy with omeprazole plus two antibiotics has been used. Due to the lack of ideal treatment and the high rates of primary resistance to nitroimidazoles, the use of clarithromycin has been adopted. OBJECTIVE To determine the Helicobacter pylori eradication rates using lansoprazole, amo...