introduction: chronic obstructive pulmonary disease (copd) patients are at increased risk of sleep-disorders. the concomitant occurrence of copd and obstructive sleep apnea hypopnea syndrome (osahs) is named overlap syndrome. this study aimed to evaluate the severity of osahs in overlap syndrome patients.materials & methods: this cross-sectional study was conducted on adult patients with forced...

Four cultivars and 21 lines of cotton were evaluated for resistance to ramulose (Colletotrichum gossypii f. sp. cephalosporioides) in a field where the disease is endemic. The seeds of each genotype were planted in 5 x 5 m plots with three replications. The lines CNPA 94101 and ‘CNPA Precoce 2’were used as standard susceptible and resistant references, respectively. The disease incidence (DI) w...

A new class of formal languages will be defined the Distributed Index Languages (DI-languages). The grammar-formalism generating the new class the DI-grammars cover unbound dependencies in a rather natural way. The place of DI-languages in the Chomsky-hierarchy will be determined: Like Aho's indexed Languages, DI-languages represent a proper subclass of Type 1 (contextsensitive languages) and p...

OBJECTIVE To analyze and compare the effectiveness and drug survival in patients with rheumatoid arthritis, as measured by 28-joint Disease Activity Score (DAS28) and Health Assessment Questionnaire-Disability Index (HAQ-DI), of tumor necrosis factor inhibitor (TNFi) monotherapy, TNFi + leflunomide (LEF), TNFi + sulfasalazine (SSZ), TNFi + other conventional synthetic disease-modifying antirheu...

A panel of 18 strains of Neisseria gonorrhoeae, known to be temporally and geographically diverse, was used to evaluate a number of typing systems, including conventional auxotyping and serotyping and the molecular methods of arbitrarily primed PCR (AP-PCR), amplified ribosomal-DNA restriction analysis (ARDRA), opa typing, and pulsed-field gel electrophoresis (PFGE). The discriminatory power of...

OBJECTIVES The aim of this study was to assess the role of the dimensionless index (DI) in a registry of patients with aortic stenosis (AS) to objectively establish prognostic DI thresholds for various degrees of AS severity. BACKGROUND DI is a classic marker of severity in AS that does not rely on the estimation of the left ventricular outflow tract (LVOT) cross-sectional area. Although DI e...

The relation between small airways disease and parenchymal destruction was investigated in lungs and lobes removed at surgery from 27 patients aged 15-70 years. Eight of the 27 patients were life-long non-smokers. The degree of small airways disease was assessed by semi-quantitative grading (SAD score) and by measuring diameter and wall thickness of membranous bronchioles. Parenchymal destructi...

We have shown earlier that a single dose of cloned defective interfering (DI) influenza A virus strongly protects mice from disease following a lethal challenge with different subtypes of influenza A virus. These animals suffered no clinical disease but experienced a subclinical infection which rendered them immune to reinfection with the same challenge virus. However, little is known about how...

BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is an independent predictor of type 2 diabetes mellitus (T2DM). Insulin resistance and beta-cell dysfunction are involved in the pathogenesis of T2DM. Insulin resistance is associated with NAFLD but little is known about beta-cell dysfunction and NAFLD. AIM We tested whether NAFLD severity is associated with insulin sensitivity and beta-cel...