Background: Small cell carcinoma of the uterine cervix is a highly malignant form of cancer in women, characterized by its high propensity for rapid extra-pelvic distant metastasis and poor prognosis. The best treatment strategy for this type of cancer is still controversial. Case presentation: We report here a case of small cell carcinoma of the uterine cervix treated by extensive total hyster...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: ca 15.3 is elevated in most patients with distant metastatic breast cancer who had prognostic information. the present study was performed to estimate predictive ability of ca 15.3 in assessment of symptomatic metastasis in patients with breast cancer. materials and methods: during five years, 159 primary breas...

INTRODUCTION Lymphangiogenesis has been reported to be important in the prognosis of several tumours. The aim of this study was to assess the correlation between lymphangiogenesis and clinicopathological prognostic parameters in patients with clear cell renal cell carcinoma. METHODS 62 patients with renal cell carcinoma were included in the study. The D2-40 antibody, assessed immunohistochemi...

The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is frequently over-expressed and serves as a prognostic marker in human cancers. However, little is known about the role of MALAT1 in gastric cancer. Here, we reported that the tissue and plasma MALAT1 levels were significantly higher in gastric cancer patients with distant metastasis (P<0.01) than patients without distant meta...

BACKGROUND In papillary and follicular thyroid cancers (PTC, FTC), nodal and distant metastasis are generally considered important determinants of recurrence and survival, respectively. However, there is no consensus about the threshold primary tumour size (PTS) for these determinants. The aim of this study was to assess size relationships for developing nodal, pulmonary, bone and overall dista...

Distant metastasis is the major cause of death in colorectal cancer (CRC). Patients at high risk of developing distant metastasis could benefit from appropriate adjuvant and follow-up treatments if stratified accurately at an early stage of the disease. Studies have increasingly recognized the role of diverse cellular components within the tumor microenvironment in the development and progressi...

Distant metastasis of thyroid carcinoma is rare, and it occurs particularly rarely in renal regions, which represent ~3% of all thyroid distant metastases, with fewer than 30 single case study reports existing in the literature. The present study (and subsequent literature review) of papillary thyroid carcinoma (PTC) reports the case of a 53-year-old male patient who presented with a left renal...

Breast tumors consist of several different tissue components. Despite the heterogeneity, most gene expression analyses have traditionally been performed without prior microdissection of the tissue sample. Thus, the gene expression profiles obtained reflect the mRNA contribution from the various tissue components. We utilized histopathological estimations of area fractions of tumor and stromal t...