نتایج جستجو برای: diuretic
تعداد نتایج: 5876 فیلتر نتایج به سال:
Plasma concentrations of immunoreactive human atrial natriuretic peptide (human ANP) were sequentially determined in 12 infants with respiratory distress syndrome (RDS) or meconium aspiration syndrome (MAS) during various phases of diuresis to elucidate the role of human ANP in the occurrence of spontaneous diuresis in the newborn. Plasma immunoreactive ANP concentrations during the diuretic as...
FUROSEMIDE (4 chloro-N[2-furyl methyl] -5-sulfamyl-anthranilic acid) (fig. 1) is a new and potent diuretic compound which is effective when given either orally or parenterally. Structurally it has in common with substituted thiazides a sulfamyl-benzene grouping. Animal studies have revealed it to be a most effective diuretic in both rats and dogs, resulting in maximum diuretic effects of up to ...
Bumetanide is a 3-aminobenzoic acid derivative. Of the several analogues having various substituents which are about equally active in test animals (3). Ostergaard elal. (5) selected 3-n-butylamino-4-phenoxy·5-sulphamyl benzoic acid (bumetanide) and studied its pharmacological properties. including its diuretic action in rats and dogs. Besides the diuretic effect bumetanide displayed hardly any...
The crude methanolic extract of the roots of Cerbera odollam Gaertn. was evaluated for its possible antinociceptive, antibacterial and diuretic activities in animal models. At the dose of 250 and 500 mg/kg body weight, the extract showed a significant antinociceptive effect in acetic acid induced writhing in mice comparable to that produced by aspirin, used as standard drug (P<0.001).The extrac...
Achyranthes aspera Linn (Amaranthaceae), commonly known as Apamarga in Ayurveda and is found as a weed that has been traditionally used for a number of ailments. The plant is indigenously used as diuretic, spermicidal, anti-allergic, cardiovascular, nephroprotective, antiparasitic, hypoglyceamic, analgesic and antipyretic. In the present study the methanolic extract of whole plant of Achyranthe...
Administration of the selective adenosine A1 receptor antagonist, CVT-124, to conscious chronically instrumented rats resulted in significant increases in urine flow rate and sodium excretion without affecting potassium excretion or renal hemodynamics. Its maximum effect was twice that of hydrochlorothiazide which was associated with a significant kaliuresis. The diuretic effect of CVT-124 was ...
Keywords: 5-amino-1,3,4-thiadiazole-2-thiol derivatives, diuretic activity, saluretic/natriuretic/carbonic anhydrase inhibition indexes, SAR,
BACKGROUND Both diuretic response and hemoconcentration are indicators of decongestion and have individually been found to predict rehospitalization after admission for acute heart failure (HF). This study examines the value of combining diuretic response and hemoconcentration to better predict patients at low risk for rehospitalization after admission for acute HF. METHODS AND RESULTS Diuret...
Loop diuretics are the most commonly used drugs in the management of pulmonary and systemic congestion in patients with acute decompensated heart failure (ADHF), as well as chronic congestive HF. The diuresis results from blockade of the Na+–K+–Cl2 co-transporter in the ascending limb of the loop of Henle. The pharmacodynamics of loop diuretics are illustrated in Figure 1, and are best describe...
Plasma concentrations of immunoreactive human atrial natriuretic peptide (human ANP) were sequentially determined in 12 infants with respiratory distress syndrome (RDS) or meconium aspiration syndrome (MAS) during various phases of diuresis to elucidate the role of human ANP in the occurrence of spontaneous diuresis in the newborn. Plasma immunoreactive ANP concentrations during the diuretic as...
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