Angiotensin II is known to act at a unique set of brain regions known as the circumventricular organs. These structures lack the normal blood-brain barrier and are therefore thought to participate in the central nervous system processing of neuroendocrine signals. We have reported that chronic treatment with the angiotensin type 1 (AT1) receptor antagonist, losartan, decreases arterial pressure...

Hypertension, a powerful risk factor for stroke and dementia, has damaging effects on the brain and its vessels. In particular, hypertension alters vital cerebrovascular control mechanisms linking neural activity to cerebral perfusion. In experimental models of slow-developing hypertension, free radical signaling in the subfornical organ (SFO), one of the forebrain circumventricular organs, is ...

The subfornical organ (SFO), one of the brain circumventricular organs, is known to mediate some of the central effects of angiotensin II related to sodium and water homeostasis. Because angiotensin II levels are altered with changes in chronic dietary salt intake, we reasoned that the actions of angiotensin II at the SFO might be involved in the regulation of arterial pressure during long-term...

We formulate the problem of shape-from-operator (SfO), recovering an embedding of a mesh from intrinsic operators defined through the discrete metric (edge lengths). Particularly interesting instances of our SfO problem include: shape-from-Laplacian, allowing to transfer style between shapes; shape-from-difference operator, used to synthesize shape analogies; and shape-from-eigenvectors, allowi...

In addition to the well-documented ability of calcitonin to lower blood calcium levels, blood-borne calcitonin may also affect neurons located outside the blood-brain barrier, e.g., in the subfornical organ (SFO), where numerous receptors for this peptide have been described. In an in vitro preparation of the rat SFO, calcitonin activated 61% of 36 neurons, only 1 neuron was inhibited, and the ...

A very simple, rapid and sensitive dispersive liquid-liquid microextraction (DLLME) followed by gas chromatography and flame ionization detection (GC-FID) was developed for the determination of phenol and carvacrol in honey samples. A mixture of 100 μl dichloromethane (extraction solvent) and 0.5 ml acetonitrile (disperser solvent) was rapidly injected into sample solution. Thereby a cloudy sol...

The polarized electric field inside piezoelectric materials has been proved to be promising technique boost the photogenerated charge separation. Herein, a novel flexible SnFe2O4/ZnIn2S4/PVDF (P-SZ) film piezophotocatalyst was successfully synthesized by combining poly vinylidene fluoride (PVDF), an organic material, with SnFe2O4...

In this paper, a simple sampling frequency offset (SFO) estimation and compensation scheme based on two phase-conjugated pilots is proposed experimentally demonstrated in an OFDM-based underwater wireless optical communication (UWOC) system. The phase shift obtained by multiplication for pilots, the results are averaged to perform more accurate estimation. experimental show that limited within ...

Abstract Dispersive liquid-liquid microextraction (DLLME) and high performance liquid chromatography – UV detection was presented for extraction determination of nandrolone testosterone in human urines. Chloroform at microliter volume level acetonitrile were used as dispersive solvents, respectively. The main advantages method are speed, enrichment factor, recovery, good repeatability solvent µ...