DNA double-strand breaks pose a significant threat to cell survival and must be repaired. In higher eukaryotes, such damage is repaired efficiently by non-homologous end joining (NHEJ). Within this pathway, XRCC4 and XLF fulfill key roles required for end joining. Using DNA-binding and -bridging assays, combined with direct visualization, we present evidence for how XRCC4-XLF complexes robustly...

Rad54 protein is a key member of the RAD52 epistasis group required for homologous recombination in eukaryotes. Rad54 is a duplex DNA translocase that remodels both DNA and protein-DNA complexes, and functions at multiple steps in the recombination process. Here we use biochemical criteria to demonstrate the existence of this important protein in a prokaryotic organism. The Sulfolobus solfatari...

As the top-down fabrication techniques for silicon-based electronic materials have reached the scale of molecular lengths, researchers have been investigating nanostructured materials to build electronics from individual molecules. Researchers have directed extensive experimental and theoretical efforts toward building functional optoelectronic devices using individual organic molecules and fab...

this article contains the views of different scholars and their researches about allah verdi khan bridge. in this brief study two important points have been highlighted. first, who is the probable constructor of the bridge and what the references tell about it. secondly, the explanation about the grave mistakes of the foundation and completion dates of the bridge and thus argument about the exa...

The paper describes the results of the EU FP7 EDGI project concerning how to extend gLite VOswith public and institutional BOINC desktop grids. Beyond simply showing the integration architecture components and services, the main emphasis is on how this integrated architecture can efficiently support parameter study applications, based on the so-calledmetajob concept created by the EDGI project....

It is common in many countries that engineers having an academic degree in Civil Engineering are appointed responsible for different tasks related to Bridge Engineering. However, there are serious questions about whether formal university courses in civil engineering could cover the needs of a bridge engineer to fulfill his or her job successfully. Regarding the recent significant advances in t...

We show that every bridgeless graph of maximum degree ∆ has a spanning d(∆ + 1)/2e-walk. The bound is optimal.

We review some techniques of resummation applied to heavy quark production in hadronic scattering and electroproduction near partonic threshold, and discuss the reduction of factorization scale dependence in resummed cross sections.