To study how the human diaphragm changes configuration during inspiration, we simultaneously measured diaphragm thickening using ultrasound and inspired volumes using a pneumotachograph. Diaphragm length was assessed by chest radiography. We found that thickening and shortening were greatest during a breath taken primarily with the abdomen. However, the degree of thickening was greater than exp...

The dome of the talus is the part that articulates with the ankle mortice formed by the lower articular surfaces of tibia and fibula. A fracture of this part of the talus may be called a dome fracture. Such fractures are not common and the significance of the original radiographic appearance is not always appreciated. Definitive treatment is therefore often unnecessarily delayed ; this has been...

OBJECTIVE Computational fluid dynamics (CFD) simulations of intracranial aneurysm hemodynamics usually adopt the simplification of the Newtonian blood rheology model. A study was undertaken to examine whether such a model affects the predicted hemodynamics in realistic intracranial aneurysm geometries. METHODS Pulsatile CFD simulations were carried out using the Newtonian viscosity model and ...

BACKGROUND BRCA1-Associated-Protein 1 (BAP1) is a dynamic tumor suppressor which, when mutated, has been associated with an increased risk of uveal melanoma, cutaneous melanoma, mesothelioma, and several other cancers. Germline BAP1 mutations have been extensively studied, where they have been found to cause hereditary cancer susceptibility. However, their sporadic counterparts, tumors that dis...

Differences exist in reproductive physiology between African buffalo (Syncerus caffer), cattle (Bos taurus) and water buffalo (Bubalus bubalis). The aim of this study was to histo-morphologically compare the anatomy of non-pregnant and pregnant uteri of buffalo and cattle. Two non-pregnant uteri and placentae of six pregnant African buffalo were used. Early placentome formation (fetal crown rum...

A general model of species diversity predicts that the latter is maximized when productivity and disturbance are balanced. Based on this model, we hypothesized that the response of bacterial diversity to the ratio of viral to bacterial production (VP/BP) would be dome-shaped. In order to test this hypothesis, we obtained data on changes in bacterial communities (determined by terminal restricti...

Marine and freshwater food webs are strongly structured by size-dependent predator−prey interactions. Predator−prey body mass ratios (PPMR) are important parameters in sizebased food-web models, but studies evaluating the temporal stability of PPMR or its relationship to predator feeding modes are scant. Using a large data set of predator−prey pairs from a diverse fish community sampled in summ...

no commissural fusion. The obstructive mechanism is related to markedly thickened, immobile cusps, characterized by the presence of disorganized myxomatous tissue. Several clinical features tend to distinguish this form of pulmonary stenosis. In each of 16 patients studied, a pulmonary ejection murmur was present, but this was not associated with an ejection click. Other features suggestive of ...

The Bossòst dome is an E–W-trending elongated structural and metamorphic dome developed in Cambro-Ordovician metasedimentary rocks in the Variscan Axial Zone of the central Pyrenees. A steep fault separates a northern half-dome, cored by massif granite, from an E–W-trending doubly plunging antiform with granitic sills and dykes in the core to the south. The main foliation is a flat-lying S1/2 s...

Recent data have shown that Dome C, on the Antarctic plateau, is an exceptional site for astronomy, with atmospheric conditions superior to those at any existing mid-latitude site. Dome C, however, may not be the best site on the Antarctic plateau for every kind of astronomy. The highest point of the plateau is Dome A, some 800 m higher than Dome C. It should experience colder atmospheric tempe...