OBJECTIVE To describe the use of a single donor corneal tissue in 3 patients with corneal pathologic conditions. METHODS A donor corneal tissue was divided into 3 parts using a microkeratome and a trephine. The anterior lamellar disc was transplanted into a patient with macular corneal dystrophy using the automated lamellar therapeutic keratoplasty technique. The posterior lamellar disc was t...

To improve visual and refractive outcomes, microkeratome-assisted lamellar keratoplasty for the treatment of keratoconus (exchange of a 9.0-mm anterior recipient lamella with a 9.0-mm donor lamella, using a 200-μm head for the former and a 300-μm head for the latter) was modified by adding a 6.5-mm incomplete full-thickness incision in the recipient bed before suturing the donor graft in place....

Department of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang Univ Abbreviations and Acronyms: CDS 1⁄4 Cornea Donor Study; DMEK 1⁄4 Descemet membrane endothelial keratoplasty; DSEK 1⁄4 Descemet stripping endothelial keratoplasty; ECD 1⁄4 endothelial cell density; EK 1⁄4 endothelial keratoplasty; FECD 1⁄4 Fuchs’ endothelial corneal dystrophy; MCMC 1⁄4 Markov chain Monte Carlo; PACE 1⁄4 pseudo...

INTRODUCTION Blindness affects 50 million individuals worldwide; a significant proportion of them require a cell or tissue-based repair or replacement strategy to mend their damaged or diseased cornea. This review will focus on the epithelial stem cell (ESC) population of the cornea, where they reside, how they are identified and what alternative cells can be used as functional substitutes. S...

PURPOSE Ocular surface disease following penetrating keratoplasty has been shown to increase patient morbidity and adversely affect graft survival. Five cases of dense central subepithelial opacification were noted in keratoplasty patients who received tissue from donors who had chemotherapy prior to death. Cancer-related deaths account for approximately 20% of the cornea donor pool. The purpos...

OBJECTIVE The lower recommended age of the donor cornea is a controversial matter. Although newborn corneas have a high endothelial cell density, there are anatomical, refractive (myopic shift) and postoperative problems. Two cases are analyzed; one had an atypical refractive result and the other an unexpectedly severe immune response. We also review the use of pediatric donor corneas in penetr...

tial for posterior dislocation of the donor corneal disc in aphakic eyes must be taken into consideration. Longer-lasting, higher-buoyancy gases (such as SF6) could be used as alternatives to air, but the possible toxic effect to endothelial cells should be elucidated. Correspondence: Dr Yoo, Cornea and External Diseases, Bascom Palmer Eye Institute, 900 NW 17th St, Miami, FL 33136 (syoo@med .m...

PURPOSE To describe endokeratophakia in which a small incision lenticule extraction (SMILE) lenticule from a myopic patient is implanted into a recipient eye through a small incision to correct hyperopia. METHODS A 23-year-old aphakic woman presented following cataract surgery to remove a childhood congenital cataract with hyperopia of +12.00 -1.50 × 155, corrected distance visual acuity of c...

Artificial corneas or keratoprostheses are intended to replace diseased or damaged cornea in the event that vision cannot be restored using donor cornea tissue. A new class of artificial cornea comprising a combination of poly (2-hydroxyethyl methacrylate) and poly (methyl methacrylate) was developed which was fabricated using a gas foaming technique. Referred to as the gas-foamed KPro, it was ...

PURPOSE To determine aerobic bacterial microbiota of the conjunctiva of cornea donors and its patterns of susceptibility to antibiotics; verify the number of corneas used for transplant and the average time of preservation in solutions with gentamicin and streptomycin; trace the profile of donors and receptors of cornea. METHODS Clinical specimens were collected from the inferior bag of the c...