نتایج جستجو برای: dorsolateral prefrontal cortex

تعداد نتایج: 151218  

Journal: :Brain : a journal of neurology 2001
V Kaasinen E Nurmi A Brück O Eskola J Bergman O Solin J O Rinne

Previous imaging studies in Parkinson's disease have focused mainly on the striatum, a region with very high dopaminergic activity. Using modern high-sensitivity 3D [(18)F]fluorodopa (Fdopa)-PET, mesocortical monoamine projections can be studied. To study the frontal monoaminergic system in unmedicated early Parkinson's disease in vivo, we examined 20 early Parkinson's disease patients (10 wome...

Journal: :Cognitive, affective & behavioral neuroscience 2010
Rebecca E Cooney Jutta Joormann Fanny Eugène Emily L Dennis Ian H Gotlib

Rumination, or recursive self-focused thinking, has important implications for understanding the development and maintenance of depressive episodes. Rumination is associated with the worsening of negative mood states, greater affective responding to negative material, and increased access to negative memories. The present study was designed to use fMRI to examine neural aspects of rumination in...

Journal: :NeuroImage 2002
Martin P Paulus Nikki Hozack Lawrence Frank Gregory G Brown

Decision-making in the presence of uncertainty is a complex process that involves both affective and cognitive factors. Both error rate and predictability have been implicated in the process of response selection during decision-making. This study examined the hypothesis that the rate of errors during decision-making differentially affects the activation in prefrontal and cingulate cortex. BOLD...

Journal: :Neuropsychologia 2005
Jacqueline N Wood Stephen G Romero Kristine M Knutson Jordan Grafman

It has been proposed that behavior is influenced by representations of different types of knowledge: action representations, event knowledge, attitudes and stereotypes. Attitudes (representations of a concept or object and its emotional evaluation) allow us to respond quickly to a given stimulus. In this study, we explored the representation and inhibition of attitudes. We show that right dorso...

Journal: :Archives of general psychiatry 2000
R E Gur P E Cowell A Latshaw B I Turetsky R I Grossman S E Arnold W B Bilker R C Gur

BACKGROUND Converging neuroanatomic, neurophysiological, and neurobehavioral evidence implicate prefrontal subregions in schizophrenia. Neuroanatomic studies with magnetic resonance (MR) imaging enable regional volume parcellation. Inconsistent reports may relate to variable methods and small samples. We attempted to resolve volume differences within sectors of the prefrontal lobe in a large sa...

Journal: :NeuroImage 2010
Trey Hedden John D. E. Gabrieli

A network of prefrontal and parietal regions has been implicated in executive control processes. However, the extent to which individual regions within this network are engaged in component control processes, such as inhibition of task-irrelevant stimulus attributes or shifting (switching) between attentional foci, remains controversial. Participants (N=17) underwent functional magnetic resonan...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
Patrick Bermudez Robert J Zatorre

A previous positron emission tomography (PET) study of musicians with and without absolute pitch put forth the hypothesis that the posterior dorsolateral prefrontal cortex is involved in the conditional associative aspect of the identification of a pitch. In the work presented here, we tested this hypothesis by training eight nonmusicians to associate each of four different complex musical soun...

Journal: :The American journal of psychiatry 2004
Sanjay J Mathew Xiangling Mao Jeremy D Coplan Eric L P Smith Harold A Sackeim Jack M Gorman Dikoma C Shungu

OBJECTIVE Few neuroimaging studies of generalized anxiety disorder have been conducted. The present study used proton magnetic resonance spectroscopy to assess concentrations of N-acetylaspartate, often considered a marker of neuronal viability, in generalized anxiety disorder patients. METHOD N-Acetylaspartate/creatine resonance ratios were measured in the left and right dorsolateral prefron...

2015
Sabrina Na Tricia Z. King Robin Morris Binjian Sun Tricia King

Behavioral studies have documented impaired working memory in childhood brain tumor survivors; however, neural mechanisms have yet to be identified using fMRI. The current study investigated BOLD response differences between twenty survivors (Mean age=23.1(4.14), 55% female) and twenty ageand gender-matched controls from the start to the end of a twenty minute 3-back task. There were no differe...

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