نتایج جستجو برای: dried blood spot test
تعداد نتایج: 1483626 فیلتر نتایج به سال:
BACKGROUND AND METHODS We describe a method for obtaining pharmacokinetics (PK) and pharmacology data from adult zebrafish in terms of mg/kg using a novel method of oral administration. Using carbamazepine (CBZ) as a test drug, we employed dried blood spot (DBS) cards to enable drug quantification for PK; and we evaluated the pharmacological anxiolytic effect using novel tank test. RESULTS Th...
References 1. Guthrie R, Susi A. A simple phenylalanine method for detecting phenylketonuria in large populations of newborn infants. Pediatrics 1963;32:338–43. 2. Williams C, Weber L, Williamson R, Hjelm M. Guthrie spots for DNA-based carrier testing in cystic fibrosis. Lancet 1988;2:693. 3. Verlingue C, Mercier B, Lecoq I, Audrezet MP, Laroche D, Travert G, et al. Retrospective study of the c...
We report a robust strategy for amino acid profiling method based on capillary electrophoresiselectrospray ionization-mass spectrometry (CE/ESI-MS) that offers a convenient platform for the direct analysis of underivatized amino acids from dried blood spot without any chemical derivatization. Sample preparation steps were simplified without derivatization. The analytical conditions with respect...
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