Abstract With the advances in organoid culture, patient-derived organoids are utilized diverse fields to broaden our understanding of conventional 2-dimensional (2D) culture methods and animal models. Patient-derived have found new applications, such as screening for patient-matching drugs, immune checkpoint mutation-target field drug screening. However, dome-shaped Matrigel drop-based using 24...

The creeping flow of a dilute (0.025 wt%) monodisperse polystyrene/polystyrene Boger fluid through a 4 : 1 : 4 axisymmetric contraction/expansion is experimentally observed for a wide range of Deborah numbers. Pressure drop measurements across the orifice plate show a large extra pressure drop that increases monotonically with Deborah number above the value observed for a similar Newtonian flui...

Multiwell plate and pipette systems have revolutionized modern biological analysis; however, they have disadvantages because testing in the submicroliter range is challenging, and increasing the number of samples is expensive. We propose a new microfluidic methodology that delivers the functionality of multiwell plates and pipettes at the nanoliter scale by utilizing drop coalescence and confin...

Biosurfactants are diverse molecules with numerous biological functions and industrial applications. A variety of environments were examined for biosurfactant-producing bacteria including soil, water and leaf surfaces. Biosurfactant production was assessed with an atomized oil assay for a large number of bacterial isolates and compared with a commonly used drop collapse assay from broth and pla...

Using an SF6 glass plate as the intracavity Kerr medium and a double-prism pair for dispersion compensation, we developed a femtosecond transform-limited passively mode-locked dye laser. Self-starting mode locking is achieved with a dilute intracavity TCVEBI saturable-absorber jet. Within a 50% power drop the tuning range is 577-606 nm. Pulse characteristics of the laser agree with theoretical ...

Isolation and screening of microorganisms from oil contaminated soil samples with biosurfactant producing ability was investigated. The biosurfactant producing ability of the microorganisms isolated from the soil samples was investigated by hemolytic assay, drop collapse test, emulsification index and methylene blue agar plate method. The best isolate was identified as Pseudomonas aeruginosa ba...

We investigate structured arrays and rings in elasticity to design elastic platonic circuits that utilise resonant phenomena. Creating ring resonators, understanding their coupling input output arrays, allows for the development of including add–drop filters (ADFs) coupled resonator (CREAs), hence we envisage integrated devices. Structured point-masses placed atop a thin plate lead highly confi...