نتایج جستجو برای: drug product
تعداد نتایج: 852628 فیلتر نتایج به سال:
The summary of product characteristics from the European Medicines Agency is a reference document on medicines in EU. It contains textual information for clinical experts how to safely use medicines, including adverse drug reactions. Using natural language processing (NLP) techniques automatically extract reactions such unstructured helps effectively and efficiently them daily practices. Such h...
Piracetam was subjected to the hydrolytic, oxidative, thermal and photolytic stress, according to ICH guideline Q1A (R2). The drug depicted degradation only in basic conditions, while it was stable to other stress conditions (acidic, neutral hydrolysis, thermal and photolytic conditions). A total of one degradation product was formed, which were separated on a BEH column employing an isocratic ...
A drug substance or drug product can be exposed to natural or artificial light during production, storage, administration and use. The great majority of drug substances and pharmaceutical excipients absorb UV and possibly visible radiation. Absorption is a first indication that a compound may participate in a photochemical process i.e. be photoreactive, which can result in its own decomposition...
BACKGROUND Because vital details of potential pharmacokinetic drug-drug interactions are often described in free-text structured product labels, manual curation is a necessary but expensive step in the development of electronic drug-drug interaction information resources. The use of nonexperts to annotate potential drug-drug interaction (PDDI) mentions in drug product label annotation may be a ...
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