نتایج جستجو برای: drug toxicity

تعداد نتایج: 637719  

2010
Troy Seidle Sally Robinson Tom Holmes Stuart Creton Pilar Prieto Julia Scheel Magda Chlebus

Acute systemic toxicity studies are carried out in many sectors in which synthetic chemicals are manufactured or used and are among the most criticized of all toxicology tests on both scientific and ethical grounds. A review of the drivers for acute toxicity testing within the pharmaceutical industry led to a paradigm shift whereby in vivo acute toxicity data are no longer routinely required in...

Journal: :eLife 2021

The discovery of a drug requires over decade intensive research and financial investments – still has high risk failure. To reduce this burden, we developed the NICEdrug.ch resource, which incorporates 250,000 bioactive molecules, studied their enzymatic metabolic targets, fate, toxicity. includes unique fingerprint that identifies reactive similarities between drug–drug drug–metabolite pairs. ...

Journal: :Revista Portuguesa de Pneumologia (English Edition) 2015

Journal: :Ukraïns’kij bìofarmacevtičnij žurnal 2018

Journal: :Archives of Disease in Childhood - Fetal and Neonatal Edition 2007

Journal: :Journal of Harmonized Research in Pharmacy 2018

Mathematical models can simulate the growth and proliferation of cells in the interaction with healthy cells, the immune system and measure the toxicity of drug and its effects on healthy tissue pay. One of the main goals of modeling the structure and growth of cancer cells is to find a control model suitable for administration among patients. In this study, a new mathematical model is designed...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید