The discovery of an effective drug treatment for attention-deficit hyperactivity disorder (ADHD) is conventionally attributed to Charles Bradley, a North American child psychiatrist who ran the family nursing home for delinquents in Rhode Island (Bradley1937). He described a case series of 30 children who received dexamphetamine, initially introduced as part of his idiosyncratic treatment for t...

There has been a major interest in the drug treatment of osteoporosis and an increase in the number of drugs available in most countries. The ideal drug (one which increases or restores bone density and trabecular connectivity) is still not available. However, in patients with relatively preserved trabecular connectivity and moderately reduced bone density, several agents have shown substantial...

Reactivation of the hepatitis B virus (HBV) can cause severe liver injury resulting in jaundice, liver failure, and death.1 This outcome continues to occur in patients receiving immunosuppressive drug therapy (ISDT) despite the ability to identify persons at risk with readily available and inexpensive blood tests for hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (...

Treatments for primary aldosteronism (PA) aim to correct or prevent the deleterious consequences of hyperaldosteronism: hypertension, hypokalemia, and direct target organ damage. Patients with unilateral PA considered fit for surgery can undergo laparoscopic adrenalectomy, which significantly decreases blood pressure (BP) and medications in most cases and cures hypertension in about 40%. Minera...

Evaluated the effectiveness of juvenile drug court for 161 juvenile offenders meeting diagnostic criteria for substance abuse or dependence and determined whether the integration of evidence-based practices enhanced the outcomes of juvenile drug court. Over a 1-year period, a four-condition randomized design evaluated outcomes for family court with usual community services, drug court with usua...

Multiple studies have shown psoriasis to be an independent risk factor for cardiovascular disease, particularly in patients with moderate-to-severe disease. Chronic, systemic inflammation is the proposed etiology for the increase in cardiovascular morbidity. Previous studies had suggested that the control of systemic inflammation with the use of methotrexate and antitumor necrosis factor agents...

OBJECTIVE To characterize the developmental status of the family-based adolescent alcohol and drug treatment specialty by identifying and discussing research and clinical advances. METHOD Selective and interpretative literature review and analysis. STUDY SELECTION Controlled trials and mechanisms of change studies of family-based treatments for adolescent alcohol and drug misuse. RESULTS ...