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OBJECTIVE To systematically review all primary care intervention studies designed to implement medication reconciliation for effects on medication discrepancies, clinical outcomes, and patient knowledge of their medications. DATA SOURCES We searched MEDLINE (1988-March 2008); Healthstar (1966-March 2008); CINAHL (1982-March 2008); EMBASE (1980-March 2008); Cochrane Database of Systematic Revi...

For the last 10 years, I’ve been on both sides of utilization review (UR). As a practicing physician, I know what it’s like to get “those calls.” As a part-time utilization reviewer, I’m usually satisfied with the interactions I have with physicians and the information I get from them. When a telephone review seems unsatisfactory, it’s often because I feel I’m speaking a different language than...

Cyclooxygenase (COX)-2-specific inhibitors were developed to circumvent the gastrointestinal toxicity of non-specific non-steroidal anti-inflammatory drugs while maintaining efficacy. However, the higher acquisition cost of COX-2-specific inhibitors has resulted in the implementation of a programme for cost containment in the Ontario public drug program. This programme consists of limited use (...

and of Theorem 7.2 on p. 206) Lang requires essentially the same result about finitely generated abelian groups. Every time he gives a proof at (unusual) length. At the first occurrence he attributes it to me, but it is a commonplace I probably learnt from Mordell. The original Diophantine geometry expected the reader to have at his fingertips that part of algebraic geometry, in the formulation...

introduction: drug utilization evaluation (due) studies are designed to assess drug usage appropriateness. dues have traditionally focused on drugs with high price tags, complicated dosage schedules, narrow therapeutic indices and regular side effects. the primary goal of the present study is to evaluate imipenem usage in bone marrow transplantation (bmt) wards. methods: the study was a prospec...

BACKGROUND Drug manufacturer rebates paid to health plans and pharmacy benefit management companies have come under increased public scrutiny. Over the past several years, numerous articles have appeared in the literature encouraging a shift to a more quality-based decision-making process for health plan drug formularies. OBJECTIVE To propose a new basis for formulary placement decisions that...