The antitumor effects of Corynebacterium parvum in a murine ovarian teratocarcinoma model depend upon a sequential activation of neutrophils and macrophages within the peritoneal cavity. We studied the sequential administration of biological response modifiers that independently activate each phase of the response. Tumor-challenged mice treated by i.p. injection of a pyridine-extracted fraction...

Dobutamine stress echocardiography (DSE) is an effective modality for determining the presence of myocardial ischemia from obstructive coronary artery disease (CAD) [1]. Several large studies have deemed DSE a largely safe imaging tool, with minimal side effects [2-5]. The most serious and rare side effects being sustained ventricular tachycardia, intracranial hemorrhage, and myocardial infarct...

Brief depolarization of cerebellar Purkinje cells was found to inhibit parallel fiber and climbing fiber EPSCs for tens of seconds. This depolarization-induced suppression of excitation (DSE) is accompanied by altered paired-pulse plasticity, suggesting a presynaptic locus. Fluorometric imaging revealed that postsynaptic depolarization also reduces presynaptic calcium influx. The inhibition of ...

A machine learning-based predictive model design space exploration (DSE) method for high-level synthesis (HLS) is presented. The method creates a predictive model for a training set until a given error threshold is reached and then continues with the exploration using the predictive model avoiding time-consuming synthesis and simulations of new configurations. Results show that the authors’ met...

Recently a dithered signed-error constant modulus algorithm (DSE-CMA) has been proposed for the purpose of low complexity implementation of constant modulus algorithm (CMA), which is widely used for blind adaptive filtering due to its LMS-like desirable robustness properties. Despite the fact that this algorithm has robustness properties closely resembling those of CMA, it is very slow in conve...

Dynamic symbolic execution, or DSE for short, has become a promising technique in software testing. However, the implementation details of DSE have not been described in depth in existing works. Although some open-source DSE tools are available nowadays, to design and implement a specific DSE tool from scratch is necessary for some reasons. To this end, we implement a Smart Fuzzing Tool for Win...

OBJECTIVE To investigate a group of patients that have a significant lesion in a single-vessel and to demonstrate whether or not the sensitivity and specificity of a dobutamine stress echocardiography (DSE) was valuable in the evaluation of myocardial viability for these patients. METHODS Twenty patients who had undergone percutaneous transluminal coronary angioplasty (PTCA) were studied. Thi...

Delonix elata L. is a Ceasalpinaceae species and is traditionally used in India for treatment of skin diseases, liver diseases and rheumatic problems. However, systematic evaluation of its wound healing activity is lacking. Thus, in the present study, we aimed to assess the wound healing activity of D. elata stem bark extract (DSE) and its isolated constituent quercetin-3-rhamnopyranosyl-(1-6) ...

OBJECTIVE To determine whether an intensive lifestyle intervention (ILI) designed to sustain weight loss and improve physical fitness in overweight or obese persons with type 2 diabetes was associated with bone loss after 4 years of follow-up. RESEARCH DESIGN AND METHODS This randomized controlled trial of intensive weight loss compared an ILI with a diabetes support and education (DSE) group...