To investigate the hypothesis that reactive oxygen metabolites are important in the pathophysiology of duodenal ulcer disease, their production by duodenal mucosal biopsy specimens was measured using luminol and lucigenin amplified chemiluminescence. Luminol chemiluminescence, expressed as background corrected median photon emission/mg/min x 10(3) (95% confidence intervals), was increased in du...

month history of moderate right upper quadrant abdominal pain. Abdominal ultrasonography revealed multiple solid liver nodules. Computed tomography (CT) of the thorax, abdomen, and pelvis confirmed liver metastases with no obvious primary tumor. Serum biochemistry showed only a mild increase in g-glutamyl transpeptidase. Carcinoembryonic antigen and CA19 –9 were increased to 60 – 80 times the n...

In a prospective controlled trial, histamine concentrations in human gastric mucosa were determined fluorometrically in 23 patients 6-11 months after selective gastric vagotomy with drainage and in patients who had undergone other types of operation for duodenal ulcer. The study was in twoparts: part I , a synchronous investigation of mucosal histamine concentrations in patients who had undergo...

A 29-yr-old homosexual man with acquired immunodeficiency syndrome presented with watery diarrhea and fever. Upper gastrointestinal endoscopy was performed to obtain duodenal aspirates and biopsies. A 4-cm submucosal mass in the gastric antrum was identified. Subsequent abdominal CT scan confirmed the presence of this antral mass. An attempt at CT guided needle biopsy was nondiagnostic. Because...

Immune responses against enterotoxigenic Escherichia coli (ETEC) were examined in Bangladeshi adults with naturally acquired disease and compared to responses in age-matched Bangladeshi volunteers who had been orally immunized with a vaccine consisting of inactivated ETEC bacteria expressing different colonization factor antigens (CFs) and the B subunit of cholera toxin. B-cell responses in duo...

BACKGROUND One of the major pathophysiological abnormalities in patients with gastro-oesophageal reflux disease is thought to involve transient lower oesophageal sphincter (LOS) relaxations. One component of the neural mechanism controlling the LOS appears to be a reflex are whose afferent limb originates in the gastric fundus. As inflammation is known to be associated with neural activation an...

AIM To investigate the natural history of lymphocytic gastritis (LG) and its relation to Helicobacter pylori infection and to coeliac disease using serology, duodenal biopsy and a small intestinal permeability test. METHOD Twenty two patients diagnosed as having LG between 1984 and 1994 were investigated by upper gastrointestinal endoscopy at which gastric and duodenal biopsy specimens were t...

The goal of research. To analyze some features peptic ulcer the stomach and duodenum in children, depending on type constitution. Material methods We examined 58 children aged 12-18 years with a diagnosis and/or duodenum, who underwent endoscopic examination, Hp was detected biopsy aero test. Results. Peptic disease more often asthenic (67.2%), less hypersthenic (17.3%) normosthenics (15.5%). V...

This case report describes an atypical case of duodenal leishmaniasis in an elderly patient not infected with human immunodeficiency virus. Investigation of this 84 year old woman with a constitutional syndrome and dysphagia revealed anaemia of chronic disorder, a high erythrocyte sedimentation rate, and polyclonal hypergammaglobulinaemia. Abdominal ultrasonography revealed thickening of the st...