The cellular basis of contracture of the palmar fascia in patients who have Dupuytren disease involves the generation of intracellular force and the transmission of this force to the surrounding tissue. A specialized cell, the myofibroblast, supposedly generates this intracellular force. Recently published studies from our laboratory demonstrated that the cytoskeleton of the myofibroblast conta...

UNLABELLED Surgery remains the gold standard in the treatment of Dupuytren contracture but is technically demanding, carries significant risk of complications, and requires prolonged recovery time. Collagenase injection is an efficacious alternative to surgery; however, contracture release often requires multiple treatments spaced a month apart. We report our experience with a new collagenase t...

Tuberculosis of the shoulder joint represents less than 1 per cent of all bone and joint tuberculosis, and affection of the subdeltoid bursa is still less common. It receives scant, if indeed any, mention in current British and American orthopaedic text-books, and since it is possible that the occasional case which does occur may be incorrectly diagnosed in the earlier stages, when treatment sh...

PURPOSE To describe changes in joint motion, sensibility, and scar pliability and to investigate the patients' expectations, self-reported recovery, and satisfaction with hand function, disability, and quality of life after surgery and hand therapy for Dupuytren disease. METHODS This prospective cohort study collected measurements before surgery and 3, 6, and 12 months after surgery and hand ...

THE surgical treatment of Dupuytren's contracture has a high subsequent incidence of fresh disease with or without digital contracture. With the increased interest in limited fasciectomy this has assumed a greater importance. This communication is concerned only with the development of fresh disease and the frequency of secondary digital contracture after radical fasciectomy. Between 1951 and 1...