deep vein thrombosis (dvt) is an important life threatening condition that is difficult to diagnose, particularly in the early stages. looking for dvt in lower limb can be considered ancillary in suspected cases of pulmonary embolism (pe) indirectly highlighting a cause and effect relationship of a single disease (i.e cause being dvt and effect is the assault on the lung vasculature). prompt an...

INTRODUCTION Mature circulating endothelial cells (CEC) and circulating endothelial progenitor cells (EPC) have been described in several conditions associated with endothelial injury. Their role in deep vein thrombosis (DVT) has not been previously evaluated. PATIENTS AND METHODS In this pilot study we evaluated the time course of CEC and EPC release after vena cava experimental DVT in mice,...

OBJECTIVE To determine the incidence of VTE in medical patients admitted to the intensive care unit (ICU) following the implementation of a standard deep venous thrombosis (DVT) prophylaxis protocol using unfractionated heparin (UFH), and to identify risk factors for DVT in these patients. METHODS We prospectively studied 123 consecutive patients admitted to the Medical ICU of King Khalid Uni...

PURPOSE Comatose elderly patients with acute neurological illness have a great risk of deep vein thrombosis (DVT). In this study, the incidence of DVT and the effectiveness of early initiation of treatment were evaluated in those patients. MATERIALS AND METHODS Total 323 patients were admitted to our ward due to neurological diseases in one year, and 43 patients, whose Glasgow Coma Scale was ...

Background Deep venous thrombosis (DVT) is a condition that occurs frequently among surgical, as well as acutely ill hospitalized medical patients, and is responsible for significant morbidity and mortality in hospitalized patients. Risk factors include older age, surgery and immobilization (as with bed rest, orthopedic casts, and sitting on long flights. Objective This study was conducted to...

BACKGROUND Although deep venous thrombosis (DVT) often complicates the clinical course in patients with cancer, few studies of the outcomes of DVT in this population have been published. Furthermore, the cost of DVT is largely undescribed. We herein report the largest study of DVT in this population to date. METHODS We reviewed the medical records of 529 consecutive cancer patients in whom DV...

In this issue of Blood, Brill and colleagues demonstrate that von Willebrand factor (VWF) release and subsequent platelet adhesion to endothelial cells are required for thrombus formation in a mouse model of deep venous thrombosis (DVT).

BACKGROUND AND PURPOSE Paradoxical embolization is frequently posited as a mechanism of ischemic stroke in patients with patent foramen ovale. Several studies have suggested that the deep lower extremity and pelvic veins might be an embolic source in cryptogenic stroke (CS) patients with patent foramen ovale. METHODS Consecutive adult patients with ischemic stroke or transient ischemic attack...

BACKGROUND Lower limb cellulitis and deep vein thrombosis share clinical features and investigation of patients with cellulitis for concurrent DVT is common. The prevalence of DVT in this group is uncertain. This study aimed to determine the prevalence of deep vein thrombosis (DVT) in patients with lower limb cellulitis and to investigate the utility of applying the Wells algorithm to this pati...