نتایج جستجو برای: eaec

تعداد نتایج: 292  

2011
Lindsey A. Edwards Mona Bajaj-Elliott Nigel J. Klein Simon H. Murch Alan D. Phillips

BACKGROUND Enteropathogenic (EPEC) and Enteroaggregative (EAEC) E. coli have similar, but distinct clinical symptoms and modes of pathogenesis. Nevertheless when they infect the gastrointestinal tract, it is thought that their flagellin causes IL-8 release leading to neutrophil recruitment and gastroenteritis. However, this may not be the whole story as the effect of bacterial adherence to IEC ...

2012
Jun-Young Kim Se-Mi Jeon Hyungjun Kim Nara Lim Mi-Sun Park Seong-Han Kim

OBJECTIVES Enteroaggregative Escherichia coli (EAEC) was recently reported as a major diarrheagenic pathogen in infant and adult travelers, both in developing and developed countries. EAEC strains are known to be highly resistant to antibiotics including quinolones. Therefore in this study we have determined the various mechanisms of quinolone resistance in EAEC strains isolated in Korea. MET...

2017
Luther A Bartelt David T Bolick Jordi Mayneris-Perxachs Glynis L Kolling Gregory L Medlock Edna I Zaenker Jeffery Donowitz Rose Viguna Thomas-Beckett Allison Rogala Ian M Carroll Steven M Singer Jason Papin Jonathan R Swann Richard L Guerrant

Diverse enteropathogen exposures associate with childhood malnutrition. To elucidate mechanistic pathways whereby enteric microbes interact during malnutrition, we used protein deficiency in mice to develop a new model of co-enteropathogen enteropathy. Focusing on common enteropathogens in malnourished children, Giardia lamblia and enteroaggregative Escherichia coli (EAEC), we provide new insig...

Journal: :Infection and immunity 1998
C Eslava F Navarro-García J R Czeczulin I R Henderson A Cravioto J P Nataro

Enteroaggregative Escherichia coli (EAEC) is an emerging cause of diarrheal illness. Clinical data suggest that diarrhea caused by EAEC is predominantly secretory in nature, but the responsible enterotoxin has not been described. Work from our laboratories has implicated a ca. 108-kDa protein as a heat-labile enterotoxin and cytotoxin, as evidenced by rises in short-circuit current and falls in...

Journal: :Japanese journal of infectious diseases 2007
Tetsuya Harada Midori Hiroi Fumihiko Kawamori Aki Furusawa Katsuhiko Ohata Kanji Sugiyama Takashi Masuda

Enteroaggregative Escherichia coli (EAEC), which is identifined by a special characteristic “stacked brick” aggregative adherence to cultured human epithelial cells (1), has been associated with acute and persistent diarrhea in children, in food poisoning diarrhea outbreaks and in overseas travelers (2). In Japan, a massive food-borne outbreak of gastrointestinal illness caused by EAEC O untype...

2011
Alexander Mellmann Dag Harmsen Craig A. Cummings Emily B. Zentz Shana R. Leopold Alain Rico Karola Prior Rafael Szczepanowski Yongmei Ji Wenlan Zhang Stephen F. McLaughlin John K. Henkhaus Benjamin Leopold Martina Bielaszewska Rita Prager Pius M. Brzoska Richard L. Moore Simone Guenther Jonathan M. Rothberg Helge Karch

An ongoing outbreak of exceptionally virulent Shiga toxin (Stx)-producing Escherichia coli O104:H4 centered in Germany, has caused over 830 cases of hemolytic uremic syndrome (HUS) and 46 deaths since May 2011. Serotype O104:H4, which has not been detected in animals, has rarely been associated with HUS in the past. To prospectively elucidate the unique characteristics of this strain in the ear...

Journal: :Journal of bacteriology 2008
Marie-Stéphanie Aschtgen Christophe S Bernard Sophie De Bentzmann Roland Lloubès Eric Cascales

Enteroaggregative Escherichia coli (EAEC) is a pathogen implicated in several infant diarrhea or diarrheal outbreaks in areas of endemicity. Although multiple genes involved in EAEC pathogenesis have been identified, the overall mechanism of virulence is not well understood. Recently, a novel secretion system, called type VI secretion (T6S) system (T6SS), has been identified in EAEC and most an...

Journal: :FEMS microbiology letters 2006
Renu Bhardwaj Siddhartha Majumdar Nirmal K Ganguly Neelam Taneja Shanta Dutta Thanadavarayan Ramamurthy Anuradha Chakraborti

Enteroaggregative Escherichia coli (EAEC) are causative agents of diarrhea, being characterized by aggregative adherence to cultured epithelial cells. In this study, phenotypic properties of EAEC were analyzed with respect to AA, hemagglutination, clump and biofilm formation, all of which are mediated by aggregative adherence fimbriae (AAF). The strains were also screened for AAF types, AAF adh...

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