The Food and Drug Administration (FDA) licensed the first 2009 influenza A (H1N1) monovalent vaccines (" H1N1 vaccines ") on September 15, 2009 (1). The H1N1 vaccines are available as a live, attenuated monovalent vaccine (LAMV) for intranasal administration and as monovalent, inactivated, split-virus or subunit vaccines for injection (MIV). The licensure and manufacturing processes for the mon...

OBJECTIVE To assess risk factors for early neonatal mortality. METHODS A population-based case-control study was carried out with 146 early neonatal deaths and a sample of 313 controls obtained among survivals of the neonate period in the south region of the city of São Paulo, in the period of 8/1/2000 to 1/31/2001. Information was obtained through home interviews and hospital charts. Hierarc...

Early Virginia (1607-24) was a nightmarish world of disease and death, perhaps unsurpassed in the annals of English colonization. Typhoid fever and dysentery visited Jamestown in recurrent epidemics killing 30 per cent or more of the colonists with each onslaught. Yet Jamestown endured because the leaders of the Virginia Company misapprehended the nexus between the estuarine environment and wat...

BACKGROUND Spontaneous supratentorial intracerebral haemorrhage is a severe, frequent, and poorly understood condition. Despite the publication of 12 randomised controlled trials on this subject, the role of surgery remains controversial and no treatment has proved to be effective. We report on a ten year prospective cohort study based on a defined population treated with or without surgery and...

a stimulation of angiogenesis by surgery. However, even if surgery does lead to an induction of angiogenesis, it is unlikely that this would translate into a worsening of mortality in such a short time period. Also, it is quite possible that age is an independent prognostic factor in breast cancer, as is the case in prostate cancer where generally younger men have more aggressive disease even i...

STUDY OBJECTIVES The aim was to examine the influence of domestic crowding and household amenities in early life on later mortality from all causes and specifically from stomach cancer, chronic obstructive pulmonary disease, and rheumatic heart disease. DESIGN This was a retrospective cohort study of people whose houses had been surveyed in 1936 and whose household size was known from the 193...

BACKGROUNDS/AIMS Identifying pancreatic cancer patients at high risk of early mortality following surgical resection for pancreatic cancer is important to make optimal treatment decisions in multidisciplinary setting. The purpose of this study was to identify the factors related to early mortality in patients who underwent pancreatic resection for pancreatic adenocarcinoma. METHODS We reviewe...