Background: Neonatal sepsis is a clinical syndrome of bacteremia characterized by systemic signs and symptoms infection in the first 28 days life. Although, Positive blood culture gold standard for diagnosis neonatal septicemia, definitive results take at least 48–72 h, resulting treatment delay. Hence certain rapid diagnostic tests such as C-reactive protein, micro erythrocyte sedimentation ra...

OBJECTIVE To study the diagnostic ability of RALIS (computerized mathematical algorithm and continuous monitoring device) to detect late onset sepsis among very low birth weight preterm neonates. METHODS Randomly chosen 24 very low birth weight infants with proven sepsis were compared to 22 infants without sepsis. The clinical parameters were retrospectively collected from the medical records...

Background: The purpose of this study was to determine the relationship between early onset sepsis and increased levels of Creactive protein (CRP) and interleukin-6 (IL-6) in cord plasma. Methods: A prospective study was conducted in 141 premature infants delivered with gestational ages of 26-35 weeks. IL-6 and CPR were measured by enzyme-linked immunoassay in the cord plasma of the neonates. A...

This study was conducted to find out the group B streptococcus colonisation of pregnant women in Kocaeli, Turkey. A culture plus individualised high-risk-based antibiotic prophylaxis was compared with high-risk-based approach alone. The screening of women was performed via vaginal and anal cultures for group B streptococcus (GBS). The maternal GBS colonisation rate was found to be 6.5%. All col...

BACKGROUND Sepsis emerges as the leading risk factor for acute kidney injury (AKI) development in critically ill patients. Much effort has been invested so far on early diagnosis of AKI using promising biomarkers. This study aimed to determine whether urine alpha1-microglobulin (α1m), a lipocaline member previously used as an indicator of proximal tubular dysfunction, can early predict the deve...

Neonatal sepsis may be categorized as early or late onset. Eighty-five percent of newborns with early-onset infection present within 24 hours, 5% present at 24-48 hours, and a smaller percentage of patients present within 48-72 hours. Onset is most rapid in premature neonates. Early onset sepsis syndrome is associated with acquisition of microorganisms from the mother. Transplacental infection ...

Neonatal septicemia continues to be one of the commonest causes of neonatal mortality and morbidity despite advances in healthcare. Neonatal sepsis may be categorized as early onset sepsis (EOS) or late onset (LOS) according to time of onset of the disease. Presence of risk factors such as low birth weight or preterm baby, febrile illness in the mother 2 weeks prior to delivery, foul smelling o...

background: exposure to endogenous hormones such as estrogen is known as a lifetime breast cancer (bc) risk factor. polymorphisms in genes that are involved in the steroidogenic process, such as cytochrome p450c17alpha ( cyp17) , affect individuals’ susceptibility to bc. in iran, the highest incident of bc is among young women. this study aimed to find prevalence of single nucleotide polymorphi...

background : alzheimer's disease (ad) is one of the most common problems for old peoples. etiology of ad is not clear, but genetic factors play a major role in determining a person's risk to develop ad. twin and family studies con-firm that ad has a genetic basis.ad genetics has been split into two broad categories: early-onset and late-onset. eo-ad cases are inherited in an autosomal dominant ...

in neonates than any other age group.1 In spite of considerable advances in antimicrobial treatment, neonatal meningitis remains a scourge with a high mortality and frequent permanent neurological sequelae. The causative agents of neonatal sepsis vary between geographical areas and with time in any particular locality. In North America and Europe, the prevalent bacterial agents of early-onset n...