BACKGROUND Spontaneous hemoperitoneum in pregnancy (SHiP) is a rare, life-threatening event, particularly relevant to women with endometriosis or deciduosis. METHODS To determine the type of lesions leading to SHiP, a literature search was conducted among all published SHiP cases. From a total of 1,339 publications, information on pathological findings at the bleeding site with histological d...

Tissue macrophages play an important role in all stages of pregnancy, including uterine stromal remodeling (decidualization) before embryo implantation, parturition, and post-partum uterine involution. The activation state and function of utero-placental macrophages are largely dependent on the local tissue microenvironment. Thus, macrophages are involved in a variety of activities such as regu...

tubal ectopic hydatidiform mole is an uncommon but very important complication of pregnancy. the clinical manifestation is the same as ectopic pregnancy and in all of the cases management was the same as tubal ectopic pregnancy. we present a case of tubal ectopic pregnancy that after laparotomy and salpingectomy, pathologic examination reported hydatidiform mole within ectopic gestational tissu...

ectopic thyroid tissue (ett) is a rare entity and a challenging differential diagnosis. this is a report of a case of a mediastinal mass that was found to be an ectopic mediastinal thyroid tissue, in a 77-year-old woman who was admitted to our hospital for breast cancer management. the mediastinal mass was identified in the postsurgical computed tomography (ct) scan of the chest and was suspect...

Partial or complete mole affects one in 1000  pregnancies.Partial mole is a rare form of ectopic pregnancy. There was a married woman,gravid 4,parity 1,abortion 1,and she had past medical history 0f right ectopic pregnancy.she had left ectopic pregnancy and was treated by laparascopic left salpyngectomy after failure of intramascular methotrexate treatment.After surgery  the pathology exam show...

Background: IL-6 is a proinflammatory and immunoregulatory cytokine to be very high in endometriosis and pelvic inflammatory disease, which are known risk factors for ectopic pregnancy(EP). The effects of IL-6 on target cells occur via the formation of a high-affinity complex with IL-6Ra that expressed in the cilia of the epithelial cells. In the present study,we compared expression of IL-6Ra i...

Abstract Study question Does abnormal serotonin homeostasis contribute to impaired endometrial decidualization in patients with recurrent implantation failure (RIF)? Summary answer Abnormal RIF, which is accompanied by decreased expression of monoamine oxidase (MAO), affects stromal cells. What known already Previous studies have found that the MAO, metabolizes serotonin, reduced endometrium an...

Dear Editor, A key event in the preparation for pregnancy is the differentiation of human endometrial stromal cells (hESCs) into epithelioid decidual cells. This process, termed decidualization, is initiated in the stromal cells of the superficial endometrial layer 9 days after ovulation. Upon decidualization, hESCs acquire the ability to resist oxidative stress, to modulate immune responses to...

Dear Editor, A key event in the preparation for pregnancy is the differentiation of human endometrial stromal cells (hESCs) into epithelioid decidual cells. This process, termed decidualization, is initiated in the stromal cells of the superficial endometrial layer 9 days after ovulation. Upon decidualization, hESCs acquire the ability to resist oxidative stress, to modulate immune responses to...

Pak J Med Sci 2015 Vol. 31 No. 3 www.pjms.com.pk 745 We read with great interest the article “Can mean platelet volume and platelet distrubition width be possible markers for ectopic pregnancy and tubal rupture?” by Ulkumen et al. in Pakistan Journal of Medical Sciences.1 We appreciate the authors for their study. We wanted to contribute to this study as it was related to our article: “The effi...