This study was undertaken to investigate the effect of aqueous extract Artemisia herba alba (Asteraceae) and procaine penicillin on healing induced defect ear cartilage. A total (25) female rats which used in this were distributed randomly into five treatment group(five animals per each). Under routine surgery, all had circular holes elastic cartilage their ears. All groups treated with local a...

background tissue engineering is used for the treatment of many diseases, and the ideal cell source for cartilage tissue engineering is chondrocytes. the main limitation of chondrocyte is the low number of cells in cartilage tissue engineering. this study investigated a suitable cell source with high proliferation rate to obtain a large number of chondrocytes. methods adult cartilage tissue sam...

Bioprinting of functional tissues could overcome tissue shortages and allow a more rapid response for treatments. However, despite recent progress in bioprinting, its outstanding ability to position cells biomaterials precise 3D manner, success has been limited, due insufficient maturation constructs into tissue. Here, novel calcium-triggered enzymatic crosslinking (CTEC) mechanism bioinks base...

conclusions both l-prp and l-prf could be used to effectively promote the healing of articular cartilage defects of the knee. results mean macroscopic scores of the treated defects were higher than the controls at all sampling times with significant differences (p < 0.05) observed between l-prf treated and control defects (10.13 vs. 8.37) and l-prp treated and control defects (10 vs. 8.5) at 4 ...

This study is aimed at the analysis of articular contact in a three-dimensional mathematical model of the human knee-joint. In particular the effect of articular contact on the passive motion characteristics is assessed in relation to experimentally obtained joint kinematics. Two basically different mathematical contact descriptions were compared for this purpose. One description was for rigid ...

smotic pressure and associated residual stresses play important oles in cartilage development and biomechanical function. The urling behavior of articular cartilage was believed to be the ombination of results from the osmotic pressure derived from xed negative charges on proteoglycans and the structural and ompositional and material property inhomogeneities within the issue. In the present stu...

Tracheal disorders can usually reduce the free lumen diameter or wall stiffness, and hence limit airflow. Trachea tissue engineering seems a promising treatment for such disorders. The required mechanical compatibility of the prepared scaffold with native trachea necessitates investigation of the mechanical behavior of the human trachea. This study aimed at mechanical characterization of human ...

Introduction The load response of a knee joint is dominated by the mechanical properties of articular cartilage, which consists of proteoglycan matrix, collagen fiber network and a fluid. The interplay of these three constituents determines the load support of articular cartilage in the joint. Finite element analysis has been widely applied to study joint mechanics. Accurate knee contact geomet...

Despite the established use of total joint replacement for the treatment of advanced degeneration of articular cartilage, component loosening due to wear and osteolysis limits the lifespan of these joint prostheses. In the present study, nanocomposites consisting of poly(vinyl alcohol) (PVA) and bacterial cellulose (BC) nanofibers were investigated as possible improved cartilage replacement mat...

A biphasic mixture model is developed that can account for the observed tension-compression nonlinearity of cartilage by employing the continuum-based Conewise Linear Elasticity (CLE) model of Curnier et al. (J. Elasticity, 37, 1-38, 1995) to describe the solid phase of the mixture. In this first investigation, the orthotropic octantwise linear elasticity model was reduced to the more specializ...