The serum proteins designated as y-globulins include all proteins of the slowest moving of the several major protein groups seen on serum electrophoresis conducted at alkaline pH (2). Among the y-globulins of normal serum are proteins of differing electrophoretic mobility (3,4), proteins with sedimentation coefficients of 6.6 S and 18 S in the ultracentrifuge (2, 3, 5, 6)) many individual antib...

In the preceding paper on the behavior of pooled normal human serum albumin in various buffers at pH 4.0 (1)) it was demonstrated that the electrophoretic pattern of albumin shows a single moving boundary in the presence of the lower fatty acids, excepting formic and acetic acid, and of certain diand tribasic organic acids. This phenomenon is probably a consequence of the interaction between th...

in this study the effects of water salinity on serum total protein and its components in grass carp were investigated. the aim of this study was to determine the effect of salinity tolerance of fish on total serum protein level and its components as an indicator of liver and kidney activity. one hundred and twenty grass carp were divided into four groups, randomly. the first three groups were r...

Investigation of the serum proteins in disease is handicapped by lack of clinically applicable methods for resolving the complex system of proteins present in blood serum into homogeneous components. The only fractionation now possible is into groups of proteins having like solubility characteristics or electrophoretic mobilities or sedimentation constants (depending upon the method employed) b...

Previous experiments (l-3) have shown that following hypophysectomy the serum globulin concentration of dogs and rats increases and at the same time the serum albumin level falls. In the above studies serum albumins and globulins were separated by salt fractionation (4). With the aim of checking our earlier results and of obtaining more detailed information regarding the changes in serum protei...

The clinical picture of acute thyroiditis 8 may be so classical that the diagnosis is obvious. However, very often, the symptomatology may be obscure. Several investigators have sought for a laboratory test, specific for the disease, to complement the clinical observations. In 1949, Werner, Quimby, and Schmidt (1) reported that six patients with thyroiditis had exceedingly low thyroidal uptakes...

Numerous investigations have been carried out during the past decades dealing with the preparation and properties of crystalline horse serum albumin. While several modifications of the classical methods and conditions for the crystallization of this protein and its components have been introduced in recent years (l-6), the electrophoretic properties of any one fraction have not yet been investi...

1. Cellular and humoral immune responses were studied in guinea-pigs fed on zinc-deficient (ZnD), Zn-adequate (control) and Zn-replete diets containing 1.25, 50 and 100 mg Zn/kg diet respectively. 2. It was found that the ZnD guinea-pigs had significantly decreased ability to elicit delayed-type hypersensitivity (DTH) response against sheep erythrocytes as compared with controls on the 9th day ...