Thermo-dynamic volume phase transition mechanisms of poly[oligo(ethylene glycol)methacrylate] (POEGMA) based microgels with poly(ionic liquid) (PIL) cross-linking moieties are investigated in detail on the basis of temperature-dependent Fourier transform infrared (FTIR) spectroscopy. The original FTIR data are further analysed by two-dimensional correlation spectroscopy (2Dcos) with the perturb...

The electrospinning technique provides non-wovens to the order of few nanometers with large surface areas, ease of functionalisation for various purposes and superior mechanical properties. Also, the possibility of large scale productions combined with the simplicity of the process makes this technique very attractive for many different applications. Biomedical field is one of the important app...

Electrospinning is an efficient method by which to produce scaffolds composed of nanoscale to microscale fibers, which are comparable to the fiber diameters of native components of the extracellular matrix. In electrospinning, a polymer solution is pumped through a syringe that is connected to a high voltage source. As a droplet forms at the tip of the needle, electrostatic repulsions form long...

Injectable biomaterials provide the advantage of a minimally invasive application but mostly lack the required structural complexity to regenerate aligned tissues. Here, we report a new class of tissue regenerative materials that can be injected and form an anisotropic matrix with controlled dimensions using rod-shaped, magnetoceptive microgel objects. Microgels are doped with small quantities ...

We present an in-flow ultrasensitive fluorescence detection of microRNAs (miRNAs) using spectrally encoded microgels. We researched and employed a viscoelastic fluid to achieve an optimal alignment of microgels in a straight measurement channel and applied a simple and inexpensive microfluidic layout, allowing continuous fluorescence signal acquisitions with several emission wavelengths. In par...

Stimuli-sensitive hydrogel microspheres or microgels are polymeric particles that consist of cross-linked three-dimensional networks. They shrink or swell significantly by expelling or absorbing large amounts of water in response to external stimuli, such as changes in temperature, pH, electric or magnetic fields. The chemical composition of the microgel determines the stimulus that can trigger...

High voltage power was used to produce jet in electrospinning. It was very difficult to study electrospinning jets by experiment, because they have high-speed and complex movements in the high-voltage electrostatic field, and the diameter of jet was very small. In this study, the software of finite element analysis was used to simulate the formation process of a stable jet in electrospinning. T...

The Poly (vinyl alcohol)/Kefirane nanofiber membrane was successfully fabricated for the firsttime using electrospinning of the polyvinyl alcohol (PVA) and Kefirane blend solution. Scanningelectron microscope (SEM), attenuated total reflectance Fourier transform infrared (ATRFT-IR), and differential scanning calorimetry (DSC) were used to characterize the electrospunPoly (vinyl alcohol)/Kefiran...

Electrospinning has emerged as an attractive technique for the fabrication of ultrafine fibres in micro-/nano-scale fineness: however, it remains a significant technological challenge to assemble aligned fibre arrays via an conventional electrospinning method due to the inherent whipping instability of the polymeric jet. We herein have first developed a simple modified electrospinning method wi...

Tissue engineering is a technique by which a live tissue can be re-constructed and one of its main goals is to associate cells with biomaterials. Electrospinning is a technique that facilitates the production of nanofibers and is commonly used to develop fibrous scaffolds to be used in tissue engineering. In the present study, a different approach for cell incorporation into fibrous scaffolds w...