One of the objectives of the Paediatric Regulation (EC) No 1901/2006, is to foster high quality ethical research on medicinal products to be used in children. To achieve this objective, the EMA is responsible for developing a European paediatric network of existing national and European networks and centres with specific expertise in research and clinical trials relating to paediatric medicines...

PSS67 DoeS HealtH-RelateD Quality of life evaluation in PSoRiaSiS MatteR? a Review of labelS of PSoRiaSiS PRoDuctS aPPRoveD by tHe fDa anD tHe eMa Acquadro C1, Perret C1, Arnould B2 1Mapi Research Trust, Lyon, France, 2Patient-Centered Outcomes Mapi, Lyon, France Objectives: Psoriasis is a papulosquamous skin disease characterized by recurring thick, itchy and dry red patches covered with silve...

OBJECTIVE An immunoglobulin A (IgA) anti-tissue transglutaminase antibody assay (anti-tTG) was compared with the conventional IgA anti-endomysium antibody assay (EMA) to assess its reliability as a screening test for celiac disease (CD) in a pediatric population. METHODS Seventy-five IgA-sufficient and 2 IgA-deficient children who were scheduled for small intestinal biopsy for the evaluation ...

Electromagnetic articulography (EMA) data provides the movement of sensors attached to different articulators of a subject when the subject is speaking. EMA data often contains missing segments due to sensor failure. In this work, we propose an equality constrained Kalman smoother to estimate the missing samples in the EMA data. We incorporate the dynamics of the articulatory movement for missi...

Perivascular epithelioid cell neoplasm/tumor (PEComa) was a relatively uncommon lesion of mesenchymal origin characterized by perivascular epithelioid cells with distinctive histological and immunohistochemical features. The occurrence in the sacral ligament was exceptional rare. Cytokeratin and epithelial membrane antigen (EMA) were considered as commonly useful epithelial markers to distingui...

N. Servant , E. Gravier , P. Gestraud , C. Laurent , C. Paccard , A. Biton , I. Brito , J. Mandel , B. Asselain , E. Barillot , P. Hupé . Institut Curie, Paris F-75248, France, INSERM U900, Paris F-75248, France, Ecole des Mines ParisTech, Fontainebleau, F-77300 France, Institut Curie, Deṕartement de Transfert, Paris F-75248, France, CNRS, UMR144, Paris F-75248, France CNRS, UMR146, Paris F-752...

BACKGROUND Alcohol and illicit drug use is more prevalent among men who have sex with men (MSM) compared to the general population and has been linked to HIV transmission in this population. Research assessing individual patterns of substance use often utilizes questionnaires or interviews that rely on retrospective self-reported information, which can be subject to recall bias. Ecological mome...

Kinematic articulatory data are important for researches of speech production, articulatory speech synthesis, robust speech recognition, and speech inversion. Electromagnetic Articulograph (EMA) is a widely used instrument for collecting kinematic articulatory data. However, in EMA experiment, one or more coils attached to articulators are possible to be mistracked due to various reasons. To ma...

In this study the measurement accuracy of the 3D EMA (Electromagnetic Articulograhy) system Carstens AG500 was evaluated using an optical motion capture system (Vicon). A custom-built container fixed the positions of the EMA sensors and the optical markers and a series of movements of the container within the EMA measurement field was recorded. The results show that (a) the very small error of ...

A commercial electromechanical actuator (EMA) is to be dynamically tested with predetermined stroke and load profiles for transient thermal and electric power behavior to validate a numerical model used for aerospace applications. The EMA will follow the stroke profile representative of a real aircraft mission duty cycle. A hydraulic press will exert a corresponding load profile onto the EMA. S...