BACKGROUND Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication of peritoneal dialysis. The etiology is unclear, but genetic predisposition may be a contributing factor. We used adenovirus-mediated gene transfer of transforming growth factor (TGF) β1 to the peritoneum in four genetically distinct laboratory mouse strains to assess differences in fibrogenic response. ...

Graham Woodrow (Chair) Renal Physician, St James’s University Hospital, Leeds Titus Augustine Consultant Surgeon, Manchester Royal Infirmary Edwina A Brown Renal Physician, Imperial College Kidney and Transplant Unit, Hammersmith Hospital Mark Cowling Consultant Radiologist, North Staffordshire University Hospitals Nevine El-Sherbini Renal Dietitian, Imperial College Kidney and Transplant Unit,...

BACKGROUND Diagnosis of encapsulating peritoneal sclerosis (EPS) is based on clinical symptoms, radiologic findings, and macroscopic or histological criteria. Two diagnostic scores for radiologic findings in computed tomography (CT) scans of patients with EPS have been established in the past (by Tarzi et al and Vlijm et al). The macroscopic appearance of EPS has previously been separated into ...

Sir, Among the complications related to PD, the most serious and life-threatening one is encapsulating peritoneal sclerosis (EPS), with a reported mortality rate of more than 60% within 4 months of diagnosis w1±3x. The poor prognosis of EPS has had a negative impact on the acceptance of PD as an adequate alternative dialysis therapy to HD. This trend has been especially prominent in Japan where...

Tuberculous peritonitis is a devastating complication of peritoneal dialysis (PD). Presentations of tuberculous peritonitis range from the common wet ascitic form to the rare fibroadhesive form, which is clinically indistinguishable from encapsulating peritoneal sclerosis. We describe a 76-year-old man on continuous ambulatory PD for three months developing wet ascitic form of tuberculous per...