نتایج جستجو برای: endocrine disrupting compounds edcs

تعداد نتایج: 280365  

Journal: :Environmental Health Perspectives 2004
Jennifer E Fox

Communication on a cellular level--defined as chemical signaling, sensing, and response--is an essential and universal component of all living organisms and the framework that unites all ecosystems. Evolutionarily conserved signaling "webs," existing both within an organism and between organisms, rely on efficient and accurate interpretation of chemical signals by receptors. Therefore, endocrin...

2014
Maren Ortiz-Zarragoitia Cristina Bizarro Iratxe Rojo-Bartolomé Oihane Diaz de Cerio Miren P. Cajaraville Ibon Cancio

Effects on fish reproduction can result from a variety of toxicity mechanisms first operating at the molecular level. Notably, the presence in the environment of some compounds termed endocrine disrupting chemicals (EDCs) can cause adverse effects on reproduction by interfering with the endocrine system. In some cases, exposure to EDCs leads to the animal feminization and male fish may develop ...

2005
Michael J. Quinn Mary Ann Ottinger Tom Porter Daniel Perez

Title of dissertation: EFFECTS OF EMBRYONIC EXPOSURE TO ANDROGEN-ACTIVE ENDOCRINE DISRUPTING CHEMICALS IN JAPANESE QUAIL Michael J. Quinn, Jr., Doctor of Philosophy, 2005 Dissertation directed by: Professor Mary Ann Ottinger Department of Animal and Avian Sciences Endocrine disrupting chemicals (EDCs) are compounds that alter the production, secretion, action, and elimination of endogenous horm...

Journal: :Proceedings. Biological sciences 2007
Leonida Fusani Daniele Della Seta Francesco Dessì-Fulgheri Francesca Farabollini

Endocrine-disrupting compounds (EDCs) have the capacity of altering the normal function of the endocrine system. EDCs have shown dramatic effects on the reproductive biology of aquatic wildlife and may affect human reproduction as well. Studies on EDCs in mammalian species have often investigated the effects of short-term, high doses on male and female reproductive physiology. However, it is di...

2013
Åke Bergman Jerrold J. Heindel Tim Kasten Karen A. Kidd Susan Jobling Maria Neira R. Thomas Zoeller Georg Becher Poul Bjerregaard Riana Bornman Ingvar Brandt Andreas Kortenkamp Derek Muir Marie-Noël Brune Drisse Roseline Ochieng Niels E. Skakkebaek Agneta Sundén Byléhn Taisen Iguchi Jorma Toppari Tracey J. Woodruff

intense scientific work has improved our understanding of the impacts of endocrine-disrupting chemicals (EDCs) on human and wildlife health, such that in 2012, the UNEP and WHO, in collaboration with international experts, have produced an updated document on EDCs, that includes scientific information on human and wildlife impacts and lists key concerns for decision makers and others concerned ...

Journal: :Endocrine reviews 2015
A C Gore V A Chappell S E Fenton J A Flaws A Nadal G S Prins J Toppari R T Zoeller

This Executive Summary to the Endocrine Society's second Scientific Statement on environmental endocrine-disrupting chemicals (EDCs) provides a synthesis of the key points of the complete statement. The full Scientific Statement represents a comprehensive review of the literature on seven topics for which there is strong mechanistic, experimental, animal, and epidemiological evidence for endocr...

2006
Gwynne Lyons

Man-made endocrine-disrupting chemicals (EDCs) present a threat to biodiversity, even in remote areas. To date, numerous wildlife species have been affected by EDCs in the environment, but it is likely that many more species are suffering effects that have not yet been reported. Impaired reproduction, damaged brain function, and deficits of the immune system are of particular concern. In order ...

2004
John D. Gordon Andrew C. Chu Michael D. Chu Charlotte L. Taylor Michael S. Denison George C. Clark

Introduction The association between the exposure and bioaccumulation of endocrine disruptor chemicals (EDCs) and their adverse effects on human and wild life populations has raised concern worldwide. Due to the detrimental effects of environmental exposure to EDCs, there is an obvious need to develop a relevant bioassay, which can both detect these chemicals, as well as provide a relevant esti...

Journal: :Annali dell'Istituto superiore di sanita 2010
Claudio Carere David Costantini Alberto Sorace Daniela Santucci Enrico Alleva

Exposure to endocrine disrupting chemicals (EDCs) is a widespread phenomenon in nature. Although the mechanisms of action of EDCs are actively studied, the consequences of endocrine disruption (ED) at the population level and the adaptations evolved to cope with chronic EDC exposure have been overlooked. Birds probably represent the animal taxon most successfully adapted to synanthropic life. H...

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